Package: 10kg/drum

Uses : Antiepileptic drug

Molecular Structure:

Product description: Product Name：Valpromide Other names: Depamide Category: pharmaceutical raw material bulk drugs api CAS NO: 2430-27-5 M.F.: C8H17NO Quality standard: YBH03002008 Edition: CP Applicable category: Antiepileptic drug; Finished dosage: Valpromide tablet; Appearance: white needle crystalline powder, lightweight, odourless, mildly bitter flavor, freely sublime; Freely soluble in ethanol, acethone and methylene dichloride, sparingly soluble in boiling water, very slightly soluble in water; Assay：not less than 99% on the anhydrous basis; Loss on drying: 1% Appearance of solution: clear and colorless; PH: 5.5~7.5 Melting point: 124~127℃; Related impurities: The peak area of total impurities ≤1.5%; Heavy metal: ≤20ppm; Packing: 10 kg/drum Advantage: High purity, Low heavy metal, Low related impurities, GMP certificate, Profession Activity & Sevice: pharmaceuticals looking for distributors, wholesale pharmaceutical generic drugs, provide lab testing service pharmaceutical Product Introduction: Valpromide (marketed as Depamide by sanofi-aventis) is a carboxamide derivative of valproic acid used in the treatment of epilepsy and some affective disorders. It is rapidly metabolised (80%) to valproic acid (another anticonvulsant) but has anticonvulsant properties itself. It may produce more stable plasma levels than valproic acid or sodium valproate and may be more effectively at preventing febrile seizures. However it is over one hundred times more potent inhibitor of liver microsomal epoxide hydrolase. This makes it incompatible with carbamazepine and can affect the ability of the body to remove other toxins. Valpromide is no safer during pregnancy than valproic acid. Valpromide is formed through the reaction of valproic acid and ammonia via an intermediate acid chloride. In pure form, valpromide is a white crystalline powder and has melting point 125-126°C. It is practically insoluble in water but soluble in hot water. It is available on the market in some European countries.