- Category :
Intermediates
- CAS NO : 738-70-5
- EC NO : 212-006-2
- Molecular Formula : C14H18N4O3
- Main Specifications : 98%
- Synonyms : trimethoprim crystalline;5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diyldiamine;Antibiotic synergist;5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine;Trimethoprim(TMP);
Package: 25kg/drum
Uses : 抗菌增效剂
Molecular Structure:
Product description:
This product is a combination of glutamic acid and trimethoprim. The formula is C14H18N4O3 C5H9NO4. It contains C14H18N4O3 C5H9NO4, which should not be less than 98.0% in dry products.
[Characters] This product is white to yellowish crystalline powder, odorless. This product is soluble in water and slightly soluble in ethanol or acetic acid.
[Inspection] The acidity of the product is 0.5 g, 30 ml water added, shaking, dissolving, determined according to law (Appendix 0631), and the pH value should be 4.5-6.5.
The clarity and color of the solution should be 0.5 g, 30 ml of water should be dissolved, and the solution should be clarified.
[Loss of Drying] Drying at 105 C to constant weight, weight reduction can not be less than 5.0% (Appendix 0831).
[Residue Ignition] Less than 0.1%.
[Content Determination] The product is about 0.3g, weighed precisely, added glacial acetic acid 20mL, dissolved by warm heat, cooled, added crystal violet indicator 1 drop, titrated with perchloric acid titration solution (0.1mol/L) until the solution appears blue, and the titration results are corrected by blank test. Per ml of perchloric acid titration solution (0.1 mol/l) is equivalent to 21.9 mg of C14H18N4O3 C5H9NO4.
[Category] Antibacterial synergists.
[Storage] Shade and keep in sealed condition.