Azelaic acid

Azelaic

Chemical Name: Azelaic acid (Azelaic Acid)

Synonym: Rhododendron acid

CAS NO. :123-99-9

Product Name: DP C9DC-98

Molecular Formula: C9H16O4

Structural Formula: HOOC (CH2) 7COOH

Nature: azelaic acid (azelaic acid; 1,9-nonanedioicaid; 1,7-heptane dicarloxylic acid) also known as azaleas acid, is an important medium and long-chain dicarboxylic acid. Crystalline appearance, fog white solid, insoluble in cold water, soluble in hot water, alcohol, ether and other polar solvents.

Specifications:

Priority Level 1 Level 2

Appearance white powder white powder white powder or yellowish

Content, wt% ≥ 99.0min ≥ 95.0min ≥ 86.0min

Melting point, oC 106.5-109 95-102 ≥ 90

Chloride ion, ppm 1max 1max 1max

Sulfate ion, ppm 5max 5max 5max

Iron, ppm 5max 5max 5max

Cu, ppm 5max 5max 5max

Water content, wt% 0.6max 0.6max 0.6max

Application:

1, for a good skin permeability, Cream Cosmetics adding azelaic acid can increase absorption through the skin functions, and a brightening of the effectiveness of Lipstick.

2, azelaic acid can inhibit microbial protein synthesis, so for Propionibacterium acnes and Staphylococcus epidermidis have antibacterial activity, can be used as anti-acne drug.

3, azelaic acid or zinc salts, and vitamin B6 compatibility, can be used for hair care products for men, hair loss disease, hormone-based treatment, and at the same time to stimulate hair growth.

Package Storage: * 25 kg paper drum.

The company uses ChineseAcademy of Sciences of the invention patents, in Professor Li Fayong University of Petroleum, Shandong University of Technology, Professor Wang Zhongwei, under the technical guidance, which lasted 11 months, the process technology development to realize process-oriented. The technology to oleic acid, hydrogen peroxide as raw materials, using thin metal catalysts, so that products from raw materials to the green, avoiding the old process of nitric acid catalyst for the production of pollution, so that our products have the following advantages: 1) the purity of the product high; 2) metal ion content is low, no harmful impurities; 3) in the pharmaceutical and cosmetic industries use a high safety factor.

Azelaic acid is a medium-and long-chain dicarboxylic acid, azelaic acid and its derivatives in a wide range of industrial uses. 9 can be used for the production of nylon polymer is nylon 69 intermediates, can increase the flexibility of unsaturated polyester; for the acid - ethylene glycol polyester modifier. Azelaic Acid 2 for the excellent cold plasticizer plasticizer suitable for artificial leather, film, sheet, wire and cable sheathing, etc., in the plastic and rubber additives in the widely used. Wang 2 Suanxin ester, decyl ester, 13 pairs of alkyl esters such as lubricating oil, viscosity-temperature characteristics of sound, viscosity index is high, especially branched-chain alcohol diester lubricating oil, its high flash point, oxidation viscosity is small, low-temperature performance is good so that it has excellent viscosity / temperature characteristics and good to add sensitivity. Is mainly used in aviation turbine engine lubricants, precision instrument oil, synthetic compressor oil, automotive engine oil, metal processing oil, synthetic grease base oil and plastics, chemical fiber and other fine chemical industries. High-purity azelaic acid or its salts added to the electrolyte in the electrolytic capacitor can be markedly improved the service life of electrolytic capacitors. With ethylene glycol / phosphoric acid / water composition of the electrolyte leakage current can be manufactured by a small spark of high current aluminum electrolyte capacitors.

In recent years, azelaic acid in the skin protection and skin treatments such as acne, improving skin aging, improve skin inflammation, skin cancer, etc. The effect of remarkable. The medical profession should play at home and abroad has been wide attention and recognition, it can effectively inhibit acne bacteria on the skin and blocking fatty acid generation, it can also slow down the growth of keratinocytes, blocking the formation of melanin, can prevent the formation of spots, lower hyperpigmentation, skin whitening agents and high-end cosmetics opened up new fields of application. 1989 by the German schering AC company has developed a 20% azelaic acid cream (trade name: Si Lian cream skinoren cream) in France, listed in 1996 the U.S. FDA approved the sale in the United States for the treatment of acne. 2002 the European Medicines Board approved four new drugs for azelaic acid. 2003 medical grade azelaic acid to obtain a medical license in China, some domestic medical institutions and pharmaceutical companies have begun to carry out the development of medical products azelaic acid, such as Zhejiang CONBA Group is actively developing azelaic acid ointment.

In addition, azelaic acid in the spices, oil, anti-corrosion agent, flocculant, fire retardant and stabilizing agents in all applications.

123-99-9