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Chemical Local Anesthetic Powder Prilocaine For Pain Relief 721-50-6

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  Post Date: Nov 20,2017
  Expiry Date: Nov 20,2018
  Detailed Description: Cas No. :721-50-6 Quantity: 1000Kilograms
Specs:foil bag
Price:1 USD Kilograms
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Chemical Local Anesthetic Powder Prilocaine For Pain Relief 721-50-6

Basic information

Product Name: Prilocaine
Synonyms: 2-(propylamino)-o-propionotoluidid;2-(Propylamino)-o-propionotoluidide;2-Methyl-alpha-propylaminopropionanilide;alpha-n-Propyl-amino-2-methylpropionanilide;alpha-n-propylamino-2-methylpropionanilide;Astra 1512;Astra 1515;astra1512
CAS: 721-50-6
MF: C13H20N2O
MW: 220.31
EINECS: 211-957-0
Product Categories: Active Pharmaceutical Ingredients;Inhibitors
Mol File: 721-50-6.mol



Description:

1. Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils L Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.

2. In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.

3.Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or 4.tertiary amine) and to hydrophobic group (aromatics) on the other side.

3.Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.


Applications:

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side.

Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.


COA
Tests Results Specifications
Description Almost white powder White or almost white powder
Solubility Complies Very soluble in alcohol and in acetone; slightly soluble in water.
Identification Complies By IR, to match with the working standard
Melting point 37.5ºC~38.9ºC 36ºC~39ºC
Water 0.03% ≤0.5%
Residue on ignition 0.05% ≤0.1%
Related compound A Not detected ≤0.01%
Related compounds Complies not more than 0.2% of any individual impurity
Complies not more than one impurity exceeds 0.1%
0.13% not more than 0.5% of total impurities
Residual solvents Not detected Dichloromethane Not more than0.06%
Not detected Ethanol Not more than0.5%
0.04% Isopropyl ether Not more than0.5%
Assay 99.67% ≥99.0%(on the anhydrous basis)


Usage and Dosage:

Infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.


Other Topical Pain Relief Powders:
 
Benzocaine CAS:94-09-7 
Benzocaine hydrochloride CAS:23239-88-5 
Tetracaine hydrochloride CAS:136-47-0
Procaine CAS:59-46-1 
Tetracaine CAS:94-24-6 
Pramoxine Hydrochloride CAS:637-58-1
Procaine HCl CAS:51-05-8
Lidocaine CAS:137-58-6
Dibucaine hydrochloride CAS:61-12-1
Prilocaine CAS:721-50-6
Propitocaine hydrochloride CAS:1786-81-8
Proparacaine hydrochloride CAS:5875-06-9
Lidocaine hydrochloride CAS:73-78-9
Articaine hydrochloride CAS:23964-57-0
Levobupivacaine hydrochloride CAS:27262-48-2
Ropivacaine hydrochloride CAS:132112-35-7
Bupivacaine CAS:2180-92-9
Bupivacaine hydrochloride CAS:14252-80-3

  CAS Registry Number:

721-50-6

  Synonyms: ;2-(propylamino)propion-o-toluidide;N-(2-Methylphenyl)-2-(propylamino)propa-namide;Prilocaine base;
  Molecular Formula: C13H20N2O
  Molecular Weight: 220.31
  Molecular Structure: 721-50-6 Prilocaine

  Company: Hengyang Desen Biotechnology Co., Ltd.     [ China ]        
  Contact: Koala
  Tel: +86-073-48164621
  Fax: 027-88608190-722
  Email: koala@desen-nutrition.com
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