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Indometacin

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  Post Date: May 08,2014
  Expiry Date: May 08,2015
  Detailed Description: Cas No. :53-86-1 Indometacin
Synonyms: Indomethacin
CAS: 53-86-1
EINECS: 200-186-5
Assay: 98.5%-100.5%.
Standard: BP2010/USP/EP
Packing: 25kg/cardboard drum
Characters: White or slightly yellow crystalline powder. Melting point 158-162 ℃. Soluble in acetone, slightly soluble in alcohol, chloroform, ethyl ether, almost insoluble in water. Tasteless, almost odorless.
Usage: Non-steroid anti-inflammatory analgesic. Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.
The product anti-inflammatory, antipyretic effect was mainly used for salicylic acid pharmaceuticals difficult to tolerate, or the effect is not significant rheumatic and arthritis, ankylosing spondylitis light, osteoarthritis, etc.


  CAS Registry Number:

53-86-1

  Synonyms: ;indomethacin methanol solution;indomethacin crystalline;indomethacin usp;indometacin;1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid;{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetate;
  Molecular Formula: C19H16ClNO4
  Molecular Weight: 357.7802
  Molecular Structure: 53-86-1 Indomethacin
  Hazard Symbols:  T+:Very toxic;
  Risk Codes: R28:;
  Safety Description: S28:;
S36/37:;
S45:;

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