Home > Offer to Sell > Pharmaceuticals and Biochemicals > Antiparasitics and antispirochete agents > Paclitaxel API 33069-62-4

Paclitaxel API 33069-62-4

Inquiry
  Post Date: Apr 26,2014
  Expiry Date: Oct 23,2014
  Detailed Description: Cas No. :33069-62-4 Payment Method: We recommend T/T or Escrow , Western Union or


1)Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane.



2)Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is also used for the prevention of restenosis.

Paclitaxel stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division. Together with docetaxel, it forms the drug category of the taxanes.




  CAS Registry Number:

33069-62-4
  Synonyms: ;7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.;taxal;taxol a;Taxol;
  Molecular Formula: C47H51NO14
  Molecular Weight: 853.9061
  Molecular Structure: 33069-62-4 Paclitaxel
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
R41:;
  Safety Description: S26:;
S36/37/39:;
S45:;

  Company: Hangzhou_Royall_Import_Export_Co_Ltd     [ China ]        
  Contact: Angela Wang
  Tel: 0086-15158015616
  Fax:
  Email: sales01@royalpharms.com
Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.