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Travoprost

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  Post Date: Jun 15,2015
  Expiry Date: Jun 14,2016
  Detailed Description: Cas No. :157283-68-6 Appearance
Colorless or pale yellow oil
Complies
Identification
(1) by HPLC
Complies
(2) by TLC
Complies
Optical rotation
+52.0º to +58.0º
54.7º
Water
Not more than 1.0%
0.79%
Limit of Ethyl acetate
Not more than 0.5%
Not detected
Residual substance
Travoprost acid: N.M.T:0.2%
Not detected
Epoxide derivative: N.M.T:0.4%
Not detected
15-epi diastereomer: N.M.T:0.1%
Not detected
5,6-trans Travoprost: N.M.T:3.5%
Not detected
15-keto derivative: N.M.T:0.3%
Not detected
Any single impurity: N.M.T:0.1%
Not detected
Total impurities: N.M.T:4.0%
Not detected
Residual solvents
Acetonitrile: N.M.T:0.04%
Not detected
Ethanol: N.M.T:0.5%
0.068%
n-Hexane: N.M.T:0.05%
Not detected
IPA: N.M.T:0.5%
0.48%
Dichloromethane: N.M.T:0.06%
Not detected
Assay
96.0% to 102.0%
98.7%

  CAS Registry Number:

157283-68-6

  Synonyms: ;(+/-)-16-(M-trifluoromethylphenoxy)Tetranorprostaglandin F2;15(S)-FLU-IPR;15(S)-FLUPROSTENOL ISOPROPYL ESTER;(+)-9ALPHA,11ALPHA,15R-Trihydroxy-16-(3-(trifluoromethyl)PHENOXY)-17,18,19,20-Tetranor-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER;9ALPHA,11ALPHA,15S-Trihydroxy-16(3-(trifluoromethyl)PHENOXY)-17,18,19,20-Tetranor-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER;(+)-FLUPROSTENOL ISOPROPYL ESTER;FLUPROSTENOL ISOPROPYL ESTER;FLU-IPR;1-methylethyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoate;
  Molecular Formula: C26H35F3O6
  Molecular Weight: 500.5477
  Molecular Structure: 157283-68-6 Travoprost
  Hazard Symbols:  F,Xi:;
  Risk Codes: 11-36/37/38:;
  Safety Description: 16-26-36:;

  Company: Lanospharma Laboratories Co.,Ltd     [ China ]        
  Contact: Peter Wen
  Tel: +86-151 8282 8191
  Fax: +86-23-63245915
  Email: sales@lanospharma.com
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