Closantel Sodium

• Post Date:

  Oct 10,2024

• Expiry Date:

  Apr 08,2025

• Detailed Description:

  Cas No. :61438-64-0

  Substance Name	Closantel Sodium
  Synonyms	* Sodium N-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-o-tolyl)-2-hydroxy-3,5-diiodobenzamidate, * EINECS 262-794-7,
  Chemical Name	Sodium N-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-o-tolyl)-2-hydroxy-3,5-diiodobenzamidate
  Molecular Formula	C23H15Cl2I2N2NaO4
  Molecular Weight	731.080
  CAS No.	61438-64-0
  Chemical Structure
  Specification	CP(V) / EP
  Pharmacodynamic Properties	Closantel is a broad-spectrum antiparasitic agent used against several species and developmental stages of trematodes, nematodes and arthropods. The anti-trematode activity of closantel is mainly used against liver fluke. The anti-nematode and anti-arthropod activity is especially used against those species which feed on blood or plasma. Closantel is an uncoupler of the mitochondrial oxidative phosphorylation resulting in inhibition of the ATP-synthesis. This induces a dramatic change in the energy metabolism which finally leads to the death of the parasite. The drug is widely used in sheep and cattle and can be used either parenterally (s.c. or i.m.) or orally for both prophylactic and therapeutic purposes and is available as drench, bolus and injectable formulations. Closantel has also been combined with mebendazole and several other benzimidazoles in drench formulations for sheep and with levamisole in a bolus for cattle.
  Storage	Keep container tightly closed in a cool, well-ventilated area.
  MSDS	Please refer to MSDS of Closantel.

• CAS Registry Number:

  61438-64-0

• Synonyms:

  ;Closantel Sodium (Patented);closantel sodium salt;n-[5-chloro-4-[(chlorophenyl)cyannomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamid sodium salt;Sodium N-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-o-tolyl)-2-hydroxy-3,5-diiodobenzamidate;sodium 2-({5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}carbamoyl)-1-hydroxy-4,6-diiodocyclohexa-2,4-diene-1-carboxylate;sodium 2-({5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}carbamoyl)-4,6-diiodophenolate;

• Molecular Formula:

  C₂₂H₁₃Cl₂I₂N₂NaO₂

• Molecular Weight:

  685.0555

• Molecular Structure:

  

• Company:

  CHANGZHOU YABANG-QH PHARMACHEM CO., LTD.     [ China ]          

• Contact:

  -

• Tel:

  0519-85095668

• Fax:

  0519-86395885

• Email:

  sales@yabang-qhpharm.com