Docetaxel anhydrous
-
- Category :
Intermediates
- CAS NO : 114977-28-5
- EC NO :
- Molecular Formula : C43H53NO14
- Main Specifications : assay:99.9
- Synonyms : docetaxel;N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyl taxol;Docetaxel Anhydrous;(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;(1beta,2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;Decetaxel anhydrous;BIND-014;Docetaxel.Anhydrous;
Package: 20kg/barrel
Uses : Used in the synthesis of pharmaceutical intermediates
Molecular Structure:
Product description:
Product Name Docetaxel anhydrous
CAS No. 114977-28-5 Quantity 20KG
Molecular Formula C43H53NO14 Manufacture Date 2015.06.17
Batch No. 20150617 Analysis Date 2015.06.28
Analysis According EP7.5 Date of Validity 2017.06.17
Item Specifications Results
Appearance White to off-white crystalline powder Conforms
Solubility Insoluble in water ,soluble in ethanol and acetone Conforms
Specific rotation ﹣38.5°～﹣41.5° -39.5°
Identification IR:The same to check sample Conforms
UV :λmax232nm Conforms
Colour reactions:postive reactions Conforms
Hplc:retention times is same as the standard sample Conforms
Tests Total impurities：≤0.8% 0.29%
Single impurity:≤0.1% 0.0702%
Impurity A：≤0.2% 0.0551%
Impurity B:≤0.3% 0.0470%
Impurity C:≤0.15% 0.0535%
Impurity E:≤0.15% 0.00%
Methylene chloride：≤0.06% 0.04%
Hexane :≤0.029% 0.002%
Acetone :≤0.5% 0.0172%
Water ：≤3.0% 2.1%
Sulphated ash :≤0.1% w/w 0.03%
Heavy metal :≤ 20ppm Conforms
Assay 98.0%～102.0% 99.7%
CN
Search Product