CN
China Suppliers > tianruipharm > Details for Valsartan
| 111Category: | Intermediates/Pharmaceutical intermediates |
|
|
| CAS NO: | 137862-53-4 | ||
| EC NO: | |||
| Molecular Formula: | C24H29N5O3 | ||
| Molecular Weight: | 435.5188 | ||
| Specification: | USP | ||
| InChI: | InChI=1/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m1/s1 | ||
| Packing: | 25kg/drum | ||
| Product description: Quick details: Chemical Name: Valsartan Molecular Formula: C24H29N5O3 Formula Weight: 435.5188 CAS NO.: 137862-53-4 Purity: 99% Characteristics:white or white crystalline powder Quality standard: USP Packaging: 25K g/drum Usage:it has the better protection effect on cardiovascular and renal. It can be routinely used by patients who are Myocardial infarction, heart failure, proteinuria, diabetes. It’s also can be combined with diuretics Description: Valsartan is an angiotensin-receptor blocker that may be used to treat a variety of cardiac conditions including diabetic nephropathy and heart failure. Valsartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system ; it competes with angiotensin II for binding to the type-1 angiotensin II receptor subtype and prevents the blood pressure increasing effects of angiotensin II. Specification: Test Items Standard Result Description White or off-white powder,odorless,slightly hygroscopy hygroscopy Qualified Solubility Free soluble in methanol and ethanol,sparingly soluble in ethyl acetate,slightly soluble in dichloromethane, particularly insoluble in water Qualified Identification IR,HPLC Must conform to reference standard Qualified Absorbance at 420nm ≤0.02 ＜0.01 Water(KF) ≤2.0% 0.4% Residue on Ignition ≤0.1% ＜0.1% Heavy Metals ≤10ppm ＜10ppm Related compounds D-valsartan ≤1.0% 0.49% Butyryl-valsartan ≤0.2% 0.02% Benzyl-valsartan ≤0.1% N.D. Any other individual impurity ≤0.1% 0.03% Total impurities(Excluding D-valsartan ) ≤0.3% 0.11% Residual Solvents Ethanol NMT5000ppm N.D Ethyl acetate NMT5000ppm 2283ppm toluene NMT890ppm 89ppm Assay(HPLC) 98.0%-102.0% 100.3% Conclusion The results conform with USP37 Our advantages: 1.High quality 2.Best price, 3..First-class service 4. High successful delivery rate |
|||
| Synonyms: | 3-methyl-2-[pentanoyl-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid;N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}valine;N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine;N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine;D-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-;Valsartan(Diovan);n-(1-oxopentyl)-n-((2'-(1h-tetrazol-5-yl)(1,1'-biphenyl)-3-yl)methyl)-l-valine; | ||
| Molecular Structure: |
 |
||
Search Product