Chlortetracycline
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- Category :
Pharmaceuticals and Biochemicals
- CAS NO : 57-62-5
- EC NO : 200-341-7
- Molecular Formula : C22H23ClN2O8
- Main Specifications : 99% up
- Synonyms : Chlortetracycline (base and/or unspecified salts);7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide;7-chlorotetracycline;Streptomyces aureofaciens antibiotic;Acronize;Acronize PD;Aureocarmyl;Aureociclin;Aureocina;Aureomicina;Aureomycin;Aureomycin A-377;Aureomycin-R;Aureomykoin;Aurofac;Aurofac 10;Biomitsin;Biomycin;Biomycin A;Biovetin;Chlorotetracycline;Chlortetracyclinum;Chrysomykine;Clortetraciclina;Duomycin;Flamycin;Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-;Feed aureomycin powder;7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide;10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-ydro-6;
Package: 25kg/drum
Uses : It is used for purulent skin diseases such as impetigo, mild small burns and infections of ulcers.
Molecular Structure:
Product description:
Product Description
The chemical name of chlortetracycline (chlortetracycline) is chlorotetracycline and the chemical formula is C22H23ClN2O8. It is a golden yellow crystalline powder produced by the fermentation of Streptomyces aureofacieus. The fermentation broth is acidified and filtered to obtain a precipitate, which is dissolved in ethanol. The crude product is obtained by acid precipitation, and the hydrochloride crystal is obtained by dissolution and salt formation.
The effect and antibacterial spectrum are the same as those of tetracycline, but the adverse reactions are the largest among tetracyclines (chlortetracycline>oxytetracycline>tetracycline).
Chlortetracycline is a tetracycline antibiotic, and many rickettsia, mycoplasma, chlamydia, atypical mycobacteria, and spirochetes are sensitive to chlortetracycline. Enterococcus is resistant to it. Over the years, due to the wide application of tetracyclines, common clinical pathogens are highly resistant to chlortetracycline, and gram-positive bacteria such as staphylococci and most enterobacteriaceae are resistant. There is cross-resistance between different varieties of chlortetracycline and tetracycline. The mechanism of action of chlortetracycline is that the drug can specifically bind to the A position of the 30S subunit of the bacterial ribosome to inhibit the growth of the peptide chain and affect the synthesis of bacterial protein.
Indications
It is used for purulent skin diseases such as impetigo, mild small burns and infections of ulcers.