Imatinib Mesylate
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- Category :
Inorganic chemicals
- CAS NO : 220127-57-1
- EC NO :
- Molecular Formula : C30H35N7O4S
- Main Specifications : In-house standard
- Synonyms : Glivec;gleevec;imatinib methanesulfonate;imatinib mesilate;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;Imatinibmesylate;Imatinib mesylate(Alpha form);
Package: 25kg/drum
Uses : Anticancer
Molecular Structure:
Product description:
Imatinib mesylate (also called Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl,
the causal agent in chronic myelogenous leukemia.
As an inhibitor of PDGFR, imatinib mesylate appears to have utility in the treatment of a variety of
dermatological diseases. Imatinib has been reported to be an effective treatment for FIP1L1-PDGFRalpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.
1. A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)
2. Echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis
3. Anticancer
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