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Lubiprostone

Lubiprostone

Category :

Intermediates

CAS NO : 136790-76-6
EC NO :
Molecular Formula : C20H32F2O5
Main Specifications : 99% up by HPLC
Synonyms : 7-[(1r,4r,6r,9r)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo[4.3.0]non-9-yl]heptanoic acid;(11a)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid;(11alpha,15R)-16,16-difluoro-15-hydroxy-9-oxo-11,15-epoxyprostan-1-oic acid;(8beta,11alpha,15R)-16,16-difluoro-15-hydroxy-9-oxo-11,15-epoxyprostan-1-oic acid;(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid;7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid;
Lubiprostone
Package: kg/bottle, 25kg/drum etc.
Uses : Prostaglandin Series
Molecular Structure:Lubiprostone 136790-76-6
Product description: Function of Lubiprostone Lubiprostone is listed on the US market and is the first chemical constipation treatment drug approved by the US Food and Drug Administration (FDA). It is also the only prescription drug approved to treat chronic idiopathic constipation in Switzerland so far. Compared with other laxatives, it not only has a good therapeutic effect on constipation, but also has a low incidence of drug resistance in long-term application, and also has the advantage of a small dose. Lubiprostone belongs to the prostaglandin class of drugs. Prostaglandins are an important class of endogenous natural products, which have multiple biological activities. Its toxicity to the human body is small, and it can exert various physiological effects when taken in a small amount. Therefore, it has attracted widespread attention in pharmacy, medicine, chemistry and biology. The structure of lubiprostone is mainly an acid with a five-membered aliphatic ring and 20 carbons with two side chains. Among them, the five-membered ring contains multiple chiral carbon atoms and two side chains. These chiral carbon atoms respectively control the configuration of each chiral center, making stereoselective synthesis difficult.
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Contact us
Company:
   Sinoway Industrial Co.LTD.
Contact:
   Xie Wen Feng
Phone:
86-592-5881089
Mobile phone:
86-13806035118
Fax:
86-592-5854960
E-mail:
xie@china-sinoway.com
Website:
http://www.china-sinoway.com
Address:
16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China
Zip Code:
361004
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