Atorvastatin Calcium
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- Category :
Pharmaceuticals and Biochemicals/Cardiovascular agents
- CAS NO : 134523-00-5
- EC NO :
- Molecular Formula : C33H33CaFNO5
- Main Specifications : atorvastatin calcium amorphous / crystalline (api)
- Synonyms : (3r,5r)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-yl-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid;Atorvastatin Acid;1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-¦Â,¦Ä-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (¦ÂR,¦ÄR)-rel-;1H-PYRROLE-1-HEPTANOIC ACID;(3S,5S)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid;calcium bis{(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate};(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid;(3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid;1H-pyrrole-1-heptanoate, 3-benzoyl-5-(4-fluorophenyl)-¦Â,¦Ä-dihydroxy-2-(1-methylethyl)-4-phenyl-, calcium salt, (betaR,deltaR)- (1:1);
Package: 10 kg/drum
Uses : Antilipemic agent
Molecular Structure:
Product description:
Product Name：atorvastatin calcium amorphous / crystalline
Other names: Lipitor, Atorvastatin, Atorvastatin Ca, Atorvastatin calcium, Atarvadel
Category: pharmaceutical raw material bulk drugs api
Cas.No.: 134523-03-8
M.F.: C66H68CaF2N4O10.3H2O
Qaulity Standard: YBH00062011
Edition: CP
Applicable category: Antilipemic agent
Finished dosage: Atorvastatin calcium tablet
Appearance: white or almost white powder, odourless, tasteless, slightly hygroscopicity;
Freely soluble in methanol,very slightly soluble in chloroform,not soluble in water,ethyl acetate,aether and cyclohexane;
Assay: 98% - 102%,on the anhydrous basis;
Loss on drying: 3%~6%
Specific rotation: -9°~-7°
Related impurities: total impurities ≤1%; individual impurity≤0.3%;
Heavy metal: ≤ 20 PPM
Packing: 10 kg/drum
Advantage: High purity, Low heavy metal, Low related impurities, GMP certificate, Profession
Activity & Sevice: pharmaceuticals looking for distributors, wholesale pharmaceutical generic drugs, provide lab testing service pharmaceutical
Product Introduction: Atorvastatin Calcium is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.
Atorvastatin was first synthesized in 1985 by Bruce Roth while working at Parke-Davis Warner-Lambert Company (now Pfizer). With 2008 sales of US$12.4 billion, Lipitor was the top-selling branded pharmaceutical in the world. U.S. patent protection was scheduled to expire in June 2011.
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