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Afatinib

Afatinib

Category :

Pharmaceuticals and Biochemicals

CAS NO : 439081-18-2
EC NO :
Molecular Formula : C24H25ClFN5O3
Main Specifications : 99 %
Synonyms : BIBW 2992;BIBW-2992;Tovok;2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-;(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide;Afatinib;(E)-N-(7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;BIBW2992;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-dime;
Afatinib
Package: According to customer's request
Uses : Afatinib is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.
Molecular Structure:Afatinib 439081-18-2
Product description: Introduction Product Name Afatinib CAS No. 439081-18-2 Synonyms BIBW 2992; BIBW-2992; Tovok; N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; (2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide; (E)-N-(7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; 2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)- Molecular Formula C24H25ClFN5O3 Molecular Weight 485.94 MDL MFCD12407405 InChI 1/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1 Appearance White to off-white solid powder Property* Purity 99 % Boiling Point (760 mmHg) 676.9 °C Density 1.381 g/cm3 Flash Point 363.2 °C *The values provided are general information and not part of the product specification. Application Main Applications Afatinib is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Packaging and Handling Grade Pharma Grade Packaging According to customer's request Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.
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Contact us
Company:
   Landz International Company Ltd.
Contact:
   Feng LING
Phone:
+86-21-58891610
Mobile phone:
Fax:
+86-21-58891720
E-mail:
info@landzltd.com
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http://www.chemnet.com/ChinaSuppliers/38495/
Address:
985 Dongfang Road, Pudong, Shanghai 200122 China
Zip Code:
200122
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