Crizotinib
-
- Category :
Pharmaceuticals and Biochemicals
- CAS NO : 877399-52-5
- EC NO :
- Molecular Formula : C21H22Cl2FN5O
- Main Specifications : 99 %
- Synonyms : (5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)methanamine;3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine;3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine;Crizotinib;PF2341066;2-pyridinamine, 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1h-pyrazol-4-yl]-;PF-02341066;
Package: According to customer's request
Uses : Crizotinib is an orally bioavailable agent belonging to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity.
Molecular Structure:
Product description:
Introduction
Product Name Crizotinib
CAS No. 877399-52-5
Synonyms PF-02341066; PF 2341066; 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine
Molecular Formula C21H22Cl2FN5O
Molecular Weight 450.34
MDL MFCD12407409
InChI 1/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1
Appearance White solid
Property*
Purity 99 %
Melting Point 202-204 °C
Boiling Point (760 mmHg) 599.2 °C
Density 1.48 g/cm3
Refractive Index n 20/D 1.67
*The values provided are general information and not part of the product specification.
Safety Data
WGK Germany 3
Application
Main Applications Crizotinib is an orally bioavailable agent belonging to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity.
Packaging and Handling
Grade Pharma Grade
Packaging According to customer's request
Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.
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