Fostriecin
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- Category :
Pharmaceuticals and Biochemicals
- CAS NO : 87810-56-8
- EC NO :
- Molecular Formula : C19H27O9P
- Main Specifications :
- Synonyms : Fostriecin [INN];Antibiotic CI 920;Antibiotic CL 1565A;CI 920;CL 1565A;Fostriecina;Fostriecina [Spanish];Fostriecine;Fostriecine [French];Fostriecinum;Fostriecinum [Latin];PD 110,161;Phosphotrienin;Pyranone phosphate;UNII-ZO1648L551;2H-Pyran-2-one, 5,6-dihydro-6-(3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl)-;(1R,3R,4Z,6Z,8E)-3,10-dihydroxy-1-{(1R,2E)-1-hydroxy-1-methyl-3-[(2S)-6-oxo-3,6-dihydro-2H-pyran-2-yl]prop-2-en-1-yl}deca-4,6,8-trien-1-yl dihydrogen phosphate;
Package: According to customer's request
Uses : an antibiotic
Molecular Structure:
Product description:
Introduction
Product Name Fostriecin
CAS No. 87860-39-7
Synonyms Phosphotrienin; Fostriecin sodium salt; CI-920; CL-1565A; NSC-339638; Pyranone phosphate; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one monosodium salt
Molecular Formula C19H26O9PNa
Molecular Weight 452.37
MDL MFCD01939908
InChI 1/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2-,6-4+,8-5-,12-11+;/t15-,16+,17+,19+;/m0./s1
Appearance Solid
Property*
Purity 99 %
Boiling Point (760 mmHg) 737.9 °C
Flash Point 400.1 °C
*The values provided are general information and not part of the product specification.
Safety Data
WGK Germany 3
RTECS UQ0600000
Application
Main Applications Fostriecin is an antibiotic which has been shown to inhibit the catalytic activity of partially purified Topo II (type II topoisomerase) in a non-competitive manner. Unlike other known inhibitors of this enzyme, fosteriecin has not been observed to cause DNA strand breaks in L1210 cells, suggesting that it does not stabilize a cleavable complex. Fostriecin has also displayed a strong capacity to inhibit protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A).
Packaging and Handling
Grade Pharma Grade
Packaging According to customer's request
Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.