Zoledronic acid hydrate
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- Category :
Pharmaceuticals and Biochemicals
- CAS NO : 165800-06-6
- EC NO :
- Molecular Formula : C5H12N2O8P2
- Main Specifications :
- Synonyms : [1-HYDROXY-(1H-IMIDAZOL-1-YL)-PHOSPHONOETHYL] PHOSPHONIC ACID MONOHYDRATE;(1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid hydrate;(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid monohydrate;PHOSPHONIC ACID, [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE]BIS-, MONOHYDRATE;ZOLEDRONIC ACID MONOHYDRATE;ZoledronicacidforInjection;[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) hydrate (1:1);
Package: According to customer's request
Uses : used in the treatment of osteoporosis
Molecular Structure:
Product description:
Introduction
Product Name Zoledronic acid hydrate
CAS No. 165800-06-6
Synonyms Zoledronic acid monohydrate; NDC-zoledronate; Zoledronate; Zometa; Reclast ; Zoledronate; CGP42446A; ZOL 446; (1-Hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid hydrate; (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid monohydrate; PHOSPHONIC ACID, [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE]BIS-, MONOHYDRATE
Molecular Formula C5H10N2O7P2.H2O
Molecular Weight 290.1
MDL MFCD08448695
InChI 1/C5H10N2O7P2.H2O/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7;/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14);1H2
Appearance Almost white powder
Property*
Purity 99 %
Melting Point 238.9 °C
Boiling Point (760 mmHg) 764 °C
Flash Point 415.8 °C
Refractive Index n 20/D 1.72
*The values provided are general information and not part of the product specification.
Safety Data
RIDADR UN 3077
WGK Germany 3
Hazard Class 9
Packing Group III
Application
Main Applications Zoledronic acid hydrate is a third-generation bisphosphonate that inhibits the prenylation of GTPases critical to the signaling events related to osteoclast-mediated bone resorption. Zoledronic acid hydrate has been used in the treatment of osteoporosis, Paget’s disease, metastatic bone disease, multiple myeloma, hypercalcemia of malignancy.
Packaging and Handling
Grade Pharma Grade
Packaging According to customer's request
Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.