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Rifaximin
Category :
Intermediates/Pharmaceutical intermediatesSynonyms :
2S-Acetyloxy-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11, 16,20,22,24,26-octamethyl-2,7-(epoxypentoeleca(1,11,13)trienimino)benzofuro[4,5-e]pyride[1,2-a]benzimidazole-1,15(2H)-dione;(2S,20S,21S,22R,23R,24S,25S,26S,27S,28E)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-1,15-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)furo[2'',3'':7',8']naphtho[1',2':4,5]imidazo[1,2-a]pyridin-25-yl acetate;(2S,16Z,18E,20S,21S,22R,24R,25S,26R,27S,28E)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-1,15-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)furo[2'',3'':7',8']naphtho[1',2':4,5]imidazo[1,2-a]pyridin-25-yl acetate;CAS NO :
80621-81-4EC NO :
Molecular Formula :
C43H51N3O11Molecular Weight :
785.8785Main Specifications :
assay not less than 98.50%InChI :
InChI=1/C43H51N3O11/c1-19-14-16-46-28(18-19)44-32-29-30-37(50)25(7)40-31(29)41(52)43(9,57-40)55-17-15-27(54-10)22(4)39(56-26(8)47)24(6)36(49)23(5)35(48)20(2)12-11-13-21(3)42(53)45-33(34(32)46)38(30)51/h11-18,20,22-24,27,35-36,39,48-51H,1-10H3,(H,45,53)/b12-11+,17-15+,21-13-/t20-,22+,23+,24+,27-,35-,36?,39+,43-/m0/s1Packing :
25kg/paper drum or 10kg/paper drumProduct description :
red-orange, hygroscopic, crystalline powder Slubility practically insoluble in water, soluble in acetone and in methanol Heavy metal not more than 20ppm Water not more than 4.5% Sulfated ash not more than 0.1% Assay 97.0% to 102.0% Related substances (1) sum of the impurities D and H: not more than 2.5 times the area of the principal peak in the chromatogram obtained with rference solution (a)(0.5%) (2)unspecified impurities:for each impurty,not more than 0.5times the area of the principal peak in the chromatogram obtained with reference solution(a)(0.1%) (3)total:not more than 5times the area of the principal peak in the chromatogram obtained with reference solution(a)(1.0%)Uses :
antibactericalMolecular Structure :
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