Tianfeng Fine Chemicals co.,Ltd.

Docetaxel anhydrous

• Category :

  Intermediates

• Synonyms :

  docetaxel;N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyl taxol;Docetaxel Anhydrous;(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;(1beta,2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;Decetaxel anhydrous;BIND-014;Docetaxel.Anhydrous;

• CAS NO :

  114977-28-5

• EC NO :

• Molecular Formula :

  C₄₃H₅₃NO₁₄

• Molecular Weight :

  807.8792

• Main Specifications :

  assay:99.9

• InChI :

  InChI=1/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32+,33-,35-,41-,42-,43+/m0/s1

• Packing :

  20kg/barrel

• Product description :

  Product Name Docetaxel anhydrous CAS No. 114977-28-5 Quantity 20KG Molecular Formula C43H53NO14 Manufacture Date 2015.06.17 Batch No. 20150617 Analysis Date 2015.06.28 Analysis According EP7.5 Date of Validity 2017.06.17 Item Specifications Results Appearance White to off-white crystalline powder Conforms Solubility Insoluble in water ,soluble in ethanol and acetone Conforms Specific rotation ﹣38.5°～﹣41.5° -39.5° Identification IR:The same to check sample Conforms UV :λmax232nm Conforms Colour reactions:postive reactions Conforms Hplc:retention times is same as the standard sample Conforms Tests Total impurities：≤0.8% 0.29% Single impurity:≤0.1% 0.0702% Impurity A：≤0.2% 0.0551% Impurity B:≤0.3% 0.0470% Impurity C:≤0.15% 0.0535% Impurity E:≤0.15% 0.00% Methylene chloride：≤0.06% 0.04% Hexane :≤0.029% 0.002% Acetone :≤0.5% 0.0172% Water ：≤3.0% 2.1% Sulphated ash :≤0.1% w/w 0.03% Heavy metal :≤ 20ppm Conforms Assay 98.0%～102.0% 99.7%

• Uses :

  Used in the synthesis of pharmaceutical intermediates

• Molecular Structure :