Sinoway Industrial Co.LTD.

Atazanavir sulphate

• Category :

  Inorganic chemicals

• Synonyms :

  Atazanavir Sulphate;Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate sulfate;methyl {(5S,10S,11S,14S)-11-benzyl-5-tert-butyl-10-hydroxy-15,15-dimethyl-3,6,13-trioxo-8-[4-(pyridin-2-yl)benzyl]-2-oxa-4,7,8,12-tetraazahexadecan-14-yl}carbamate sulfate (1:1) (non-preferred name);

• CAS NO :

  229975-97-7

• EC NO :

• Molecular Formula :

  C₃₈H₅₄N₆O₁₁S

• Molecular Weight :

  802.934

• Main Specifications :

  99% up

• InChI :

  InChI=1/C38H52N6O7.H2O4S/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28;1-5(2,3)4/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47);(H2,1,2,3,4)/t29-,30-,31+,32+;/m0./s1

• Packing :

  25kg/drum

• Product description :

  Atazanavir sulfate CAS 229975-97-7 Atazanavir is an hiv-1 protease inhibitor that selectively inhibits the specific processing of viral Gag and gag-pol polyproteins in hiv-1 infected cells, thereby blocking the formation of mature virion, and is used in combination with other antiretroviral drugs for the treatment of hiv-1 infection. Application: Atazanavir sulfate is a scientific reagent, widely used in molecular biology, pharmacology and other scientific research.Azanavir is a nitrogen heteropeptide inhibitor of hiv-1 protease.Azanavir sulfate selectively inhibits the specific processing of viral Gag and gag-pol proteins in hiv-1 infected cells, thereby blocking the formation of mature viruses by Chemicalbook.In vitro antiviral activity: the average 50% inhibitory concentration (IC50) of azanavir on a large number of laboratory-and clinically isolated hiv-1 virus strains transplanted in peripheral blood monocytes, macrophages, cem-ss cells and MT2 cells was 2 ~ 5nM without human serum.

• Uses :

  Pharmaceutical Intermediate

• Molecular Structure :