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Docetaxel trihydrate
Category :
Inorganic chemicalsSynonyms :
DocetaxelTrihydrate;Benzenepropanoic acid, -[[(1,1-dimethylethoxy)carbonyl]amino]--hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (betaS)-, hydrate (1:3);Docetaxel.Trihydrate;Docetaxel(Trihydrate);CAS NO :
148408-66-6EC NO :
Molecular Formula :
C43H59NO17Molecular Weight :
861.9251Main Specifications :
99% upInChI :
InChI=1/C43H53NO14.3H2O/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45;;;/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52);3*1H2/t26-,27-,28+,30-,31+,32?,33-,35-,41+,42-,43+;;;/m0.../s1Packing :
25kg/drumProduct description :
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used mainly for the treatment of breast, ovarian, and non-small cell lung cancer. Docetaxel has an approved claim for treatment of patients who have locally advanced, or metastatic breast or non small-cell lung cancer who have undergone anthracycline-based chemotherapy and failed to stop cancer progression or relapsed.Administered as a one-hour infusion every three weeks generally over a ten cycle course, docetaxel is considered better than doxorubicin, paclitaxel and fluorouracil as a cytotoxic antimicrotubule agent.Uses :
Pharmaceutical IntermediateMolecular Structure :
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