Sinoway Industrial Co.LTD.

Griseofulvin

• Category :

  Inorganic chemicals

• Synonyms :

  grisovin;7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione;(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione;(2R,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione;(2S,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione;(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohexane]-3,4'-dione;Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione,7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'R-trans)-;(+)-Griseofulvin;

• CAS NO :

  126-07-8

• EC NO :

  204-767-4

• Molecular Formula :

  C₁₇H₁₉ClO₆

• Molecular Weight :

  354.7822

• Main Specifications :

  99%

• InChI :

  InChI=1/C17H19ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h7-8,12H,5-6H2,1-4H3/t8-,12?,17+/m1/s1

• Packing :

  1kg/bag, 5kg/bag, or as per customers’ requirements.

• Product description :

  Product Information Product Name: Griseofulvin Cas No.: 126-07-8 Molecular Formula: C17H17ClO6 Molecular Weight: 352.77 Uses: Griseofulvin is used to treat skin infections such as jock itch, athlete's foot, and ringworm; and fungal infections of the scalp, fingernails, and toenails. Specification: Test items Specifications (BP2011 /EP7.0) Description A white or yellow white microfine powder Identification A: IR B:Colour test (a white-red colour develops) Acidity Not more than 1.0ml of 0.02M sodium hydroxide is required. Solubility Practically insoluble in water,freely soluble in dimethyl formamide and in tetrachloroethane,slightly soluble in ethanol and in methanol. Specific optical rotation Calculated with reference to the dried substance +354°~+364° Particle size 95% no more than 5um(larger particles which may occasionally exceed 30um) Melting point It melts at about 220℃ Appearance of solution The solution is clear Not more intensely coloured than reference solution Y4 Related substances: Dechologriseofulvin Less than 0.60 Dehydrogriseofulvin Less than 0.15 Substances soluble in light petroleum NMT 0.20% Loss on drying NMT 1.00% Sulphated ash NMT 0.20% Abnormal toxicity Five mice orals,none of the mice dies within 48h Assay(anhydrous substance) 97.0% to 102.0%

• Uses :

  API, pharmaceutical

• Molecular Structure :