LONYE TECHNOLOGY LIMITED

Colistin sulfate

• Category :

  Food and Feed additives

• Synonyms :

  Colistin Sulphate;n-[3-amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide sulfate;N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methyloctanamide sulfate (1:1);N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide;belcomycin;

• CAS NO :

  1264-72-8

• EC NO :

  215-034-3

• Molecular Formula :

  C₅₂H₉₈N₁₆O₁₃

• Molecular Weight :

  1155.4339

• Main Specifications :

  2% 4% 10%

• InChI :

  InChI=1/C52H98N16O13/c1-9-29(6)11-10-12-40(71)59-32(13-19-53)47(76)68-42(31(8)70)52(81)64-35(16-22-56)44(73)63-37-18-24-58-51(80)41(30(7)69)67-48(77)36(17-23-57)61-43(72)33(14-20-54)62-49(78)38(25-27(2)3)66-50(79)39(26-28(4)5)65-45(74)34(15-21-55)60-46(37)75/h27-39,41-42,69-70H,9-26,53-57H2,1-8H3,(H,58,80)(H,59,71)(H,60,75)(H,61,72)(H,62,78)(H,63,73)(H,64,81)(H,65,74)(H,66,79)(H,67,77)(H,68,76)/t29?,30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,41+,42+/m1/s1

• Product description :

  Product name	Colistin sulfate
  CAS No.:	1264-72-8
  Specification:	2%, 4%, 10%
  Principle:	The positive free amino group of the active ingredients is combined with the negative polyphosphate in the cell membrane as well as with nucleic acid to form insoluble compounds, resulting in cell membrane damage, permeability improvement of cell membrane and leakage of intracellular phosphate and nucleic acid to kill bacteria.
  Character	It has strong anti-bacteria activity against Gram-negative bacteria. Low incidence of anti-drug reactions No drug cross-resistance with other antibiotics. It can not be particularly absorbed in alimentary tract. It is highly safe and in lack of residue. It is especially manufactured for healthy foods. It promotes growth and increases feed utilization rate.
  Precaution:	1） It can not be mixed with aureomycin, terramycin, zinc bacitracin-colistin premix and olaquindox for feeding use. 2） The dosage used to treat contagious enteritis is doubled to the highest dosage above.

• Molecular Structure :