Hunan Dinuo Pharmaceuical Co.,Ltd

atorvastatin calcium amorphous / crystalline 134523-03-8

• Category :

  Pharmaceuticals and Biochemicals/Cardiovascular agents

• Synonyms :

  ATORVASTATIN CA;[r-(r*, r*)]-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylaminocarbonyl)-1h-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid calcium salt;1h-pyrrole-1-heptanoicacid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methy calciumsalt(2:1),(r-(r*,r*))-lethyl)-3-phenyl-4-((phenylamino)carbonyl);delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-betcalci1h-pyrrole-1-heptanoicaci;pd134298-38a;ATORVASTATINCALCUIM;calcium (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-p ropan-2-yl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate;1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt (2: 1), (R-(R*,R*))-;1H-Pyrrole-1-heptanoic acid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt (2: 1);(R-(R*,R*))-, Atorvastatin calcium;Atorvastatin calcium (USAN);Atorvastatin calcium salt;Atorvastatin calcium [USAN];C08078;Calcium (betaR,deltaR)-2-(p-fluorophenyl)-beta,delta-dihydroxy-5-isopr opyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate (1:2);CI-981;D00887;DRG-0321;Lipibec;Lipitor;Lipitor (TN);LS-136974;PD 134298-38A;Prevencor;Sortis;Tahor;Torvast;YM-548;Atorvastatin Calsium;(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5-Dihydroheptanoic Acid,calcium salt;(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5�CDihydroheptanoic Acid,calcium salt;L-4;(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5�CDihydroheptanoic Acid,calcium salt(L-4);beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt(2:1);Atorvastatin Calcium Anhydrous;

• CAS NO :

  134523-03-8

• EC NO :

• Molecular Formula :

  C₆₆H₆₈Ca₂F₂N₄O₁₀

• Molecular Weight :

  1195.4197264

• Main Specifications :

  atorvastatin calcium amorphous / crystalline 134523-03-8

• InChI :

  InChI=1/2C33H35FN2O5.2Ca.2H/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);;;;/q;;;+2;;/p-2/t2*26-,27-;;;;/m11..../s1/r2C33H35FN2O5.CaH2.Ca/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);1H2;/q;;;+2/p-2/t2*26-,27-;;/m11../s1

• Packing :

  10kg/drum

• Product description :

  Product Name：atorvastatin calcium amorphous / crystalline Other names: Lipitor, Atorvastatin, Atorvastatin Ca, Atorvastatin calcium, Atarvadel Category: pharmaceutical raw material bulk drugs api Cas.No.: 134523-03-8 M.F.: C66H68CaF2N4O10.3H2O Qaulity Standard: YBH00062011 Edition: CP Applicable category: Antilipemic agent Finished dosage: Atorvastatin calcium tablet Appearance: white or almost white powder, odourless, tasteless, slightly hygroscopicity; Freely soluble in methanol,very slightly soluble in chloroform,not soluble in water,ethyl acetate,aether and cyclohexane; Assay: 98% - 102%,on the anhydrous basis; Loss on drying: 3%~6% Specific rotation: -9°~-7° Related impurities: total impurities ≤1%; individual impurity≤0.3%; Heavy metal: ≤ 20 PPM Packing: 10 kg/drum Advantage: High purity, Low heavy metal, Low related impurities, GMP certificate, Profession Activity & Sevice: pharmaceuticals looking for distributors, wholesale pharmaceutical generic drugs, provide lab testing service pharmaceutical Product Introduction: Atorvastatin Calcium is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body. Atorvastatin was first synthesized in 1985 by Bruce Roth while working at Parke-Davis Warner-Lambert Company (now Pfizer). With 2008 sales of US$12.4 billion, Lipitor was the top-selling branded pharmaceutical in the world. U.S. patent protection was scheduled to expire in June 2011.

• Uses :

  Antilipemic agent

• Molecular Structure :