Zhejiang University Sunny Technology Co.,Ltd.

Tiamulin

• Category :

  Pharmaceuticals and Biochemicals/Antibiotic and antimicrobial agents

• Synonyms :

  Tiamuline Hydrogen Fumarate;((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE;DENAGARD;,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles;14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate;14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato;81723hfu;dynamutilin;sandoz81723hfu;Tiamulin Fumarate;(4R,5S,6S,8R,9aS,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);(3aS,4R,5S,6S,8R,9R,9aR)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);

• CAS NO :

  55297-96-6

• EC NO :

  259-581-6

• Molecular Formula :

  C₃₂H₅₁NO₈S

• Molecular Weight :

  609.8142

• Main Specifications :

  EP/USP/Feed Grade

• InChI :

  InChI=1/C28H47NO4S.C4H4O4/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28;5-3(6)1-2-4(7)8/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t19?,20-,22+,24-,25-,26+,27-,28-;/m0./s1

• Packing :

  25kg drum

• Product description :

  TIAMULIN

  COMMON NAME: Tiamulin Hydrogen Fumarate

   

  MOLECULAR FORMULAR: C28H47NO4S·C4H4O4

   

  MOLECULAR WEIGHT: 609.82

   

  SPECIFICATION

  Items   Technical Specifications	Specifications
  Appearance	White crystal powder
  Identification	IR-spectrum/HPLC retention times
  pH	From 3.1 to 4.1
  Loss on drying	Not more than 0.5%
  Heavy Metals (ppm)	Not more than 10
  Fumarate assay	18.6-19.4%
  Assay (HPLC)	98.0-102.0%

   

  INDICATION

  Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms such as streptococci, staphylococci and against mycoplasmas and serpulina (Treponema) hyodysenteriae. A number of Shigella, Klebsiella and E. coli are also quite susceptible to this agent. Some anaerobic species including Bacteroides fragilis and Clostridium perfringens with no exception are sensitive to tiamulin.

  Tiamulin acts bacteriostatically. The biochemical basis for the antibacterial action is inhibition of protein synthesis, by binding to 70S ribosomes.

  Tiamulin is used for prevention and control of mycoplasmal diseases such as enzootic pneumonia and chronic respiratory disease in pigs and poultry; and swine dysentery, porcine colonic spirochaetosis and porcine proliferative enteropathy.

   

  CAUTION

  Dont use together with polyether ionophores such as Monesin, Salinomycin etc.

  Dont touch with eyes and skin.

   

  STORAGE

  Keep in dry ,cool places; Seal the bag after use.

   

  PACKAGE

  25 Kg drum

• Uses :

  Antibiotic for Animal Use

• Molecular Structure :