Hangzhou Yunnuo Chemical Co., Ltd.

Imidazole

• Category :

  Intermediates/Pharmaceutical intermediates

• Synonyms :

  Glyoxaline;Imidazole Glyoxaline;Imidazole, ULTROL Grade;1,3-diazole;IMZ;1H-imidazole;

• CAS NO :

  288-32-4

• EC NO :

  206-019-2

• Molecular Formula :

  C₃H₄N₂

• Molecular Weight :

  68.0773

• Main Specifications :

  White crystalline powder；Purity:99%

• InChI :

  InChI=1/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

• Packing :

  25kg/fiber drum or as request

• Product description :

  Imidazole (CAS#288-32-4), a white crystalline powder, purity up to 99%, is stable to acid and has antioxidant properties, and its derivatives are widely found in nature, such as histamine, histidine, benzimidazole, etc. Its acyl compounds can be used as acylating agents, reacting with pyrrole to produce 1-acetylpyrrole, and then ketones and aldehydes can be produced by using Gerstmann's reagent and reducing agents. Besides, purine derivatives can be obtained after the ring condensation of imidazole and pyrimidine. Imidazole also has a catalytic effect, such as accelerating the hydrolysis of enzymes, which is under study. In addition, imidazole is slightly more basic than pyrazole and can produce stable salts, such as picrates and nitrates, which can also be used for the purification of His-tagged proteins in metal chelate affinity chromatography (IMAC). What's more, imidazole is an important fine chemical raw material, mainly used in the synthesis of pharmaceuticals and pesticides and epoxy resin curing agent. Used as a pesticide raw material for boric acid preparation synergist, preparation of insecticides and fungicides, is the pesticide strobilurin, miconazole, such as fungicide intermediates; can also be used as a curing agent for epoxy resins, can improve the bending, tensile, compression, and other mechanical properties of the product, to improve the electrical properties of the insulation, to improve the resistance to the chemical properties of the chemical agents, widely used in computers, electrical appliances; as a copper antirust agent used in the printed circuit version and the Integrated circuits. In medicine, it is used in imidazole antifungal drugs, it is one of the main raw materials of diclobenzimidazole, econazole, ketoconazole, clotrimazole, etc. It is also used in the manufacture of antimycotic agents, hypoglycemic therapeutic drugs, artificial plasma, trichomonas therapeutic drugs, bronchial asthma therapeutic drugs, anti-spotting agents, etc. In addition to this, it is also used as raw materials for urea-formaldehyde resin curing agent, photographic drugs, adhesives, coatings, rubber vulcanizing agent, antistatic agent, etc. and as an In addition, it is also used as raw materials and organic synthesis intermediates for urea-formaldehyde resin curing agent, adhesive, coating, rubber vulcanizing agent, antistatic agent, etc. It is also widely used as preservative for fruit. Imidazole is also used as the raw material of imidazole derivatives such as glyburide, carbonyl diimidazole, etc., as an effective buffer in the range of pH 6.2-7.8, used for titration of aspartic acid and glutamic acid, as well as cobalt determination, used for anti-metabolism, anti-histamine. The regular package is cardboard drums lined with plastic bags, sealed and stored in a cool and dry place.

• Uses :

  an important fine chemical material, used in the preparation of imidazole antifungal drugs；one of the main raw materials of bis-chlorobenzimidazole, econazole, ketoconazole, clotrimazole, etc；used in the manufacture of antimycotic agents, hypoglycemic the

• Molecular Structure :