Landz International Company Ltd.

Afatinib

• Category :

  Pharmaceuticals and Biochemicals

• Synonyms :

  BIBW 2992;BIBW-2992;Tovok;2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-;(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide;Afatinib;(E)-N-(7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;BIBW2992;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-dime;

• CAS NO :

  439081-18-2

• EC NO :

• Molecular Formula :

  C₂₄H₂₅ClFN₅O₃

• Molecular Weight :

  485.9384

• Main Specifications :

  99 %

• InChI :

  InChI=1/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+

• Packing :

  According to customer's request

• Product description :

  Introduction Product Name Afatinib CAS No. 439081-18-2 Synonyms BIBW 2992; BIBW-2992; Tovok; N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; (2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide; (E)-N-(7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; 2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)- Molecular Formula C24H25ClFN5O3 Molecular Weight 485.94 MDL MFCD12407405 InChI 1/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1 Appearance White to off-white solid powder Property* Purity 99 % Boiling Point (760 mmHg) 676.9 °C Density 1.381 g/cm3 Flash Point 363.2 °C *The values provided are general information and not part of the product specification. Application Main Applications Afatinib is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Packaging and Handling Grade Pharma Grade Packaging According to customer's request Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.

• Uses :

  Afatinib is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.

• Molecular Structure :