Guangxi QILI Pharmaceutical Co.,ltd.

Oxytetracycline Hydrochloride

• Category :

  Pharmaceuticals and Biochemicals

• Synonyms :

  oxytetracycline hydrochloride;5-hydroxytetracycline hydrochloride;(4s-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride;Oxytetracycline HCL;OTC HCL;(2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride;(3E,11S)-3-[amino(hydroxy)methylidene]-4a,6,7,11,12-pentahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride;(4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1);Oxytertracycline HCL;10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-monohydrochloride;

• CAS NO :

  2058-46-0[2]

• EC NO :

  218-161-2

• Molecular Formula :

  C₂₂H₂₅ClN₂O₉

• Molecular Weight :

  496.8949

• Main Specifications :

  Oxytetracycline Hydrochloride tablets: 0.25g/tablet(1mg=1000ug).

• InChI :

  InChI=1/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1

• Product description :

  This product is a broad-spectrum antibacterial agent, many rickettsia, mycoplasma, chlamydia, helix, amoeba, and some are also sensitive to this product. enterococcus is resistant to it. Other like actinomycetes, bacillus anthracis, monocytosis listeria, clostridium, slave card bacteria genera, vibrio, Gibraltar, campylobacter, yell, bacteria, etc are sensitive to it. Alias: Oxytetracycline, Oxytetracycline Hydrochloride, Oxycycin, Stevacin Molecular formula: C22H24N2O9·HCl Molecular weight: 496.89 CAS No.: 2058-46-0[2] Molecular structure: Characters: Its hydrochloride is yellow crystalline powder, odorless, bitter taste; Have led to wet; With light color gradient, are prone to damage failure in alkali solution. Soluble in water, slightly soluble in ethanol, insoluble in chloroform or ether. pharmacologic action: Antibacterial spectrum and application and tetracycline are the same. This product of intestinal infection, including amoebic dysentery, curative effect is slightly better than tetracycline. Close cross resistance with tetracycline. Adaptives: Antibacterial spectrum and application and tetracycline are the same. This product of intestinal infection, including amoebic dysentery, curative effect is slightly better than tetracycline. Cautions: See tetracycline. Closely cross resistance with tetracycline. Spec: Oxytetracycline Hydrochloride tablets: 0.25g/tablet(1mg=1000ug). 2 security term 1. After contact with eyes, rinse immediately with plenty of water and seek medical advice. 2. Wear suitable protective clothing, gloves and goggles or mask. 3. components Preparation by soil Streptomyces. Molecular formulaC22H25ClN2O9. Raw materials for activated carbon used for the production of the drug methanol sulfuric acid, hydrochloric acid, terramycin, hydrochloric acid. 4 Characters This product is a yellow crystalline powder. Odourless, slightly bitter taste; Micro has led to wet; Dark in the sun, in the alkali soluble easy damage failure. This product is soluble in water, slightly soluble in ethanol, insoluble in chloroform or ether. Take this product than the curl, precision said, dissolved with hydrochloric acid solution (9-1000) and diluted into each 1 ml contains 10 mg of solution, avoid light place for 1 hour, determined in accordance with the law, than the curl of the to - 188 degrees - 200 degrees. 5. main Uses Of gram positive bacteria and meningococcal, gonococcus gram-negative bacteria such as antimicrobial activity. [3] 6. adaptives 1. This product can be used as a selection of the following diseases with drugs: (1) rickettsial disease, including typhus epidemic and endemic typhus and rocky mountain hot, tropical typhus and Q fever. (2) the mycoplasma infection. (3) the chlamydial infection, including psittacosis, sexually transmitted disease, lymphatic meat tooth is swollen, salpingitis, nonspecific urethritis, cervicitis and trachoma. (4) relapsing fever. (5) the undulant disease. (6) cholera. (7) tularemia. Plague. (8) (9) soft chancre. Treatment is required for a undulant disease and plague and aminoglycoside joint applications. 2. This product due to the common pathogenic bacteria drug resistance is serious, sensitive, this product only in pathogenic bacteria could be selected as a drug, e. coli, this product is sensitive to gas enterbacteriaceae, wizard acinetobacter, shigella, haemophilus influenzae (limited to the respiratory tract infection) and klebsiella species (limited to the respiratory tract and urinary tract infection) such as gram negative bacillus infection. This product should not be used for any type of staphylococcus aureus or hemolytic streptococcus infection. 3. This product can be used for allergic to penicillin kind of tetanus, gas gangrene, jas, syphilis, gonorrhea, leptospirosis and actinomycetes, listeria infection patients. 4. Can be used for acute intestinal amebiasis and, in patients with severe acne as adjuvant therapy.

• Uses :

  Of gram positive bacteria and meningococcal, gonococcus gram-negative bacteria such as antimicrobial activity. [3]

• Molecular Structure :