Guangxi QILI Pharmaceutical Co.,ltd.

Vitamin B12

• Category :

  Pharmaceuticals and Biochemicals

• Synonyms :

  cyano-5,6-dimethylbenzimidazole-cobalamin;Cyanocobalamin;VB12;5,6-dimethyl-1-(3-o-phosphono-alpha-d-ribofuranosyl)-1h-benzimidazolmonoes;

• CAS NO :

  68-19-9

• EC NO :

  200-680-0

• Molecular Formula :

  C₆₃H₈₈CoN₁₄O₁₄P

• Molecular Weight :

  1355.3652

• Main Specifications :

• InChI :

  InChI=1/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31?,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1/rC63H89CoN14O14P/c1-30-20-40-41(21-31(30)2)77(29-73-40)58-53(87)54(42(27-79)90-58)92-93(88,89)91-32(3)26-72-50(86)18-19-60(8)38(22-47(69)83)57-63(11)62(10,25-49(71)85)37(14-17-46(68)82)52(78(63)64-28-65)34(5)56-61(9,24-48(70)84)35(12-15-44(66)80)39(74-56)23-43-59(6,7)36(13-16-45(67)81)51(75-43)33(4)55(60)76-57/h20-21,23,29,32,35-38,42,53-54,57-58,79,87H,12-19,22,24-27H2,1-11H3,(H2,66,80)(H2,67,81)(H2,68,82)(H2,69,83)(H2,70,84)(H2,71,85)(H,72,86)(H,88,89)/q+1/p-1/b39-23+,51-33-,52-34-/t32?,35-,36-,37-,38+,42-,53-,54-,57-,58+,60-,61+,62+,63+/m1/s1

• Product description :

  Vitamin B12, Anacobin, is the only Vitamin that contains metal elements. The nature of Vitamin B12 are microbial synthesis, higher plants and animals cannot make Vitamin B12, Vitamin B12 is a kind of intestinal secretions (internal factor) need to help can be absorbed only a Vitamin. Some people due to gastrointestinal abnormalities, lack the endogenous factor, even a dietary source of abundant can be pernicious anemia. Basically do not have Vitamin B12 in the plant foods. It long stay in the gut, it takes about three hours (most water-soluble Vitamin it only takes a few seconds) to be absorbed. Main physiological functions of Vitamin B12 is involved in making red blood cells in the bone marrow, prevent pernicious anemia; To prevent damage to the brain. Basic information Product name: Vitamin B12 Molecular formula: C63H88CoN14O14P Alias Vitamin B12,Anacobin,Berubigen,Cobalin,Cyanocobalamin,Dobetin,Vibicon EINECS: 200-680-0 Molecular weight: 1355.37 An overview of the Vitamin B12 or cyanide cobalt element, also called cobalt amine is a kind of composed of porphyrin compounds containing cobalt B vitamins. Initially found taking the liver can control the symptoms of pernicious anemia, after 20 years of research, in 1948 was isolated from the liver of a control effect of pernicious anemia with red crystal material, named as Vitamin B12, determine its structural formula in 1963. In 1973 to complete the synthetic. Vitamin B12 in the body because of the combination group is different, but there are a variety of forms, such as: cobalamin, cyanokit, cobalt amine and 5 '- cobalt deoxyadenosine amine, which is the activity of Vitamin B12, also is the main form of existence in the blood. Vitamin B12 is found so far in B vitamins at the latest one. Vitamin B12 is a department of polycyclic compounds containing trivalent cobalt, four reduction of pyrrole ring together into a goo Lin large ring (similar to porphyrin), is the core of Vitamin B12 molecules. So are the class of compounds containing this kind of ring goo moiety. Vitamin B12 for light red acicular crystal, soluble in water and ethanol, at pH 4.5 ~ 5.0 under the condition of weak acid is the most stable, strong acid (pH < 2) or break down in the alkaline solution, when it is heated to a certain degree damage, loss of high temperature disinfection is small, but a short time in strong light or ultraviolet light easy broken. Ordinary cooking process loss of about 30%. Structural features Glutamic acid and methyl pancreatic is two kinds of coenzyme form of vitamin B12. In cobalt Lin above the ring plane cobalt ions with 5, 6 and 2 methyl phenyl imidazole N - 3, and 5 'at the bottom of the plane - C5' deoxyadenosine. General application of B12, and cobalt ions is connected to the CN, called cobalt cyanogen ammonia, is a green crystal.

• Molecular Structure :