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DSIP (Delta sleep-inducing peptide) for sell

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  Post Date: Jul 25,2015
  Expiry Date: Jan 21,2016
  Detailed Description: Cas No. :CAS:62568-57-4
DSIP (Delta sleep-inducing peptide) for sell

Basic Info.

Model NO.:62568-57-4DSIP


Specification:1mg/Vial or 2mg/Vial


CAS:62568-57-4


Sequence:Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu


Formula:C35h48n10o15


Molecular Weight:848.81


Purity:99.0%Min


Export Markets:Global


Additional Info.


Packing:Secure and Discreet Package


Standard:USPDSIP


Origin:Wuhan China


Production Capacity:5000kits/Month


Product Description

Delta sleep-inducing peptide(DSIP)
Delta sleep-inducing peptide(DSIP) Specification: 1mg/vial or 2mg/vial
Delta sleep-inducing peptide(DSIP) CAS#: 62568-57-4?
Delta sleep-inducing peptide(DSIP) Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Delta sleep-inducing peptide(DSIP) Formula: C35H48N10O15
Delta sleep-inducing peptide(DSIP) Molecular Weight: 848.81
Delta sleep-inducing peptide(DSIP) Purity: 99.0%min
Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
DSIP has stress-protective, antiseizure, [and immunomodulating effects. It has been demonstrated that DSIP have significant geroprotective effect. K. V. Sudakov views DSIP as one of the 4 main substances, responsible for the stress-resistance of the organism, another 3 being substance P, prolactin and beta-endorphin. Main mechanism of action of exogeniously injected DSIP seems to be very strong GABA-ergic effect.



Product Description

DSIP (Delta sleep-inducing peptide)


Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.


Its aminoacid sequence is r-l-Gly-Gly-Asp-Ala-Ser-Gly-Glu. However, it is the only neuropeptide in history whose gene is unknown, raising serious questions regarding the actual existence of this peptide in nature.


DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif: N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C


It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.


In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through α 1 receptors in rats. It is unknown where DSIP is synthesized.


In vitro it has been found to have a low molecular stability with a half life of only 15 minutes due to the action of a specific aminopeptidase-like enzyme. It has been suggested that in the body it complexes with carrier proteins to prevent degradation, or exists as a component of a large precursor molecule, but as yet no structure or gene has been found for this precursor.?


Evidence supports the current belief that it is regulated by glucocorticoids.




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