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DSIP (Delta sleep-inducing peptide) for sell

  • Post Date:

    Jul 25,2015
  • Expiry Date:

    Jan 21,2016
  • Detailed Description:

    Cas No. :CAS:62568-57-4 Quantity: 1000Kilograms
    Specs:E-mail:judy26@ycphar.com
    Payment Method: T/T,Western Union,MoneyGram

    Basic Info.

    Model NO.:62568-57-4DSIP


    Specification:1mg/Vial or 2mg/Vial


    CAS:62568-57-4


    Sequence:Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu


    Formula:C35h48n10o15


    Molecular Weight:848.81


    Purity:99.0%Min


    Export Markets:Global


    Additional Info.


    Packing:Secure and Discreet Package


    Standard:USPDSIP


    Origin:Wuhan China


    Production Capacity:5000kits/Month


    Product Description

    Delta sleep-inducing peptide(DSIP)
    Delta sleep-inducing peptide(DSIP) Specification: 1mg/vial or 2mg/vial
    Delta sleep-inducing peptide(DSIP) CAS#: 62568-57-4?
    Delta sleep-inducing peptide(DSIP) Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
    Delta sleep-inducing peptide(DSIP) Formula: C35H48N10O15
    Delta sleep-inducing peptide(DSIP) Molecular Weight: 848.81
    Delta sleep-inducing peptide(DSIP) Purity: 99.0%min
    Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
    DSIP has stress-protective, antiseizure, [and immunomodulating effects. It has been demonstrated that DSIP have significant geroprotective effect. K. V. Sudakov views DSIP as one of the 4 main substances, responsible for the stress-resistance of the organism, another 3 being substance P, prolactin and beta-endorphin. Main mechanism of action of exogeniously injected DSIP seems to be very strong GABA-ergic effect.



    Product Description

    DSIP (Delta sleep-inducing peptide)


    Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.


    Its aminoacid sequence is r-l-Gly-Gly-Asp-Ala-Ser-Gly-Glu. However, it is the only neuropeptide in history whose gene is unknown, raising serious questions regarding the actual existence of this peptide in nature.


    DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif: N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C


    It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.


    In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through α 1 receptors in rats. It is unknown where DSIP is synthesized.


    In vitro it has been found to have a low molecular stability with a half life of only 15 minutes due to the action of a specific aminopeptidase-like enzyme. It has been suggested that in the body it complexes with carrier proteins to prevent degradation, or exists as a component of a large precursor molecule, but as yet no structure or gene has been found for this precursor.?


    Evidence supports the current belief that it is regulated by glucocorticoids.




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  • CAS Registry Number:

    CAS:62568-57-4
  • Company:

    Wuhan Yuancheng Technology Development Co., Ltd.         
  • Contact:

    cathy
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    86-27-50756029
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    judy26@ycphar.com
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