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Dehydroisoandrosterone

Inquiry
  Post Date: Jan 21,2015
  Expiry Date: Jul 20,2015
  Detailed Description: Cas No. :53-43-0 Quantity: 1000Kilograms
Specs:white powder
Price:350 USD Metric Tons
Payment Method: T/T
Detailed Product Description

CAS 53-43-0 Oral DHEA Anabolic Steroids Dehydroisoandrosterone Powder



Product Name:
Dehydroisoandrosterone
Alias:
3beta-Hydroxy-5-androsten-17-one

CAS NO.:
53-43-0
Purity:
99%

Appearance:
white powder
Application:
Nutritional Supplements ;Steroid and Hormone






Dehydroisoandrosterone

Usage: Dehydroepiandrosterone (DHEA, more correctly didehydroepiandrosterone), also known as androstenolone or prasterone (INN), as well as 3β-hydroxyandrost-5-en-17-one or 5-androsten-3β-ol-17-one, is an important endogenous steroid hormone.It is the most abundant circulating steroid hormone in humans, in whom it is produced in the adrenal glands, the gonads, and the brain, where it functions predominantly as a metabolic intermediate in the biosynthesis of the androgen and estrogen sex steroids. However, DHEA also has a variety of potential biological effects in its own right, binding to an array of nuclear and cell surface receptors, and acting as a neurosteroid.





Quick Detail:



Product name:Dehydroisoandrosterone (DHEA)
Other name:3beta-Hydroxy-5-androsten-17-one
CAS :53-43-0
EINECS : 200-175-5


Molecular formula: C19H28O2
Molecular weight: 288.43
Melting point 149-151 ℃.
Assay 98% min.
Pharmaceutical Intermediates;Steroids;17-Ketosteroids;Biochemistry;Hydroxyketosteroids;Nutritional Supplements;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API





Ddescription and .Applications:



DHEA is produced naturally in the human body, but the long term effects of its use are largely unknown. In the short term, several studies have noted few adverse effects. In a study by Chang et al., DHEA was administered at a dose of 200 mg/day for 24 weeks with slight androgenic effects noted. Another study utilized a dose up to 400 mg/day for 8 weeks with few adverse events reported. A longer term study followed patients dosed with 50 mg of DHEA for 12 months with the number and severity of side effects reported to be small. Another study delivered a dose of 50 mg of DHEA for 10 months with no serious adverse events reported.



As a hormone precursor, there has been a smattering of reports of side effects possibly caused by the hormone metabolites of DHEA.



It is not known whether DHEA is safe for long-term use. Some researchers believe DHEA supplements might actually raise the risk of breast cancer, prostate cancer, heart disease, diabetes, and stroke. DHEA may stimulate tumor growth in types of cancer that are sensitive to hormones, such as some types of breast, uterine, and prostate cancer. DHEA may increase prostate swelling in men with benign prostatic hyperplasia (BPH), an enlarged prostate gland.



DHEA is a steroid hormone. High doses may cause aggressiveness, irritability, trouble sleeping, and the growth of body or facial hair on women. It also may stop menstruation and lower the levels of HDL ("good" cholesterol), which could raise the risk of heart disease. Other reported side effects include acne, heart rhythm problems, liver problems, hair loss (from the scalp), and oily skin. It may also alter the body's regulation of blood sugar.



In women with adrenal insufficiency and the healthy elderly there is insufficient evidence to support the use of DHEA.
1 .Strength:Evidence is inconclusive in regards to the effect of DHEA on strength in the elderly.
In middle-aged men, no statistically significant effect of DHEA supplementation on lean body mass, strength, or testosterone levels was found in a randomized placebo-controlled trial.
2. Memory :DHEA supplementation has not been found to be useful for memory function in normal middle aged or older adults. It has been studied as a treatment for Alzheimer's disease, but there is no evidence that it is effective.
3. Cardiovascular disease and risk of death: A review in 2003 found the then-extant evidence sufficient to suggest that low serum levels of DHEAS may be associated with coronary heart disease in men, but insufficient to determine whether DHEA supplementation would have any cardiovascular benefit.
4. Lupus :There is some evidence of short term benefit in those with systemic lupus erythematosus but little evidence of long term benefit or safety.
Anabolic effects include growth of muscle mass and strength, increased bone density and strength, and stimulation of linear growth and bone maturation.
Androgenic effects include maturation of the sex organs, particularly the penis and the formation of the scrotum in the fetus, and after birth (usually at puberty) a deepening of the voice, growth of the beard and axillary hair. Many of these fall into the category of male secondary sex characteristics.




Packaging & Delivery Process:



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  CAS Registry Number:

53-43-0
  Synonyms: ;3beta-Hydroxy-5-androsten-17-one;Dehydroepiandrosterone;trans-Dehydroandrosterone;Prasterone;Hydroxyandrostenone;3b-hydroxyandrost-5-en-17-one;DHEA;3-Hydroxyandrost-5-en-17-one;3?Hydroxyandrost-5-en-17-one;Dehydroepian drosterone;Andro-3B-Ol-17-One;Androstenolone;3Beta-Hydroxyandrost-5-En-17-One;3B-Hydroxy-5-Androsten-17-One;Dehydroisoandrosterone;Hydroxyandrost-5-En-17-One;(3Beta,8Xi,9Xi,14Xi)-17-Oxoandrost-5-En-3-Yl Acetate;(3Β,9Ξ,14Ξ)-3-Hydroxyandrost-5-En-17-One;Androst-5-En-17-One,3-Beta-Hydroxy Acetate;DHEA Dehydroepiandrosterone;
  Molecular Formula: C19H28O2
  Molecular Weight: 288.4244
  Molecular Structure: 53-43-0 (+)-Dehydroisoandrosterone
  Risk Codes: 36/37/38:;
  Safety Description: S24/25:;

  Company: Wuhan hezhong chemical manufature Co.,Ltd     [ China ]        
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  Tel: 13971676705
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