Home > Offer to Sell > Intermediates > Pharmaceutical intermediates > Muscle Building Pharmaceutical Raw Materials Dapoxetine Hydrochloride
Muscle Building Pharmaceutical Raw Materials Dapoxetine Hydrochloride
Inquiry
| Post Date: | Jun 29,2015 |
| Expiry Date: | Jun 28,2016 |
| Detailed Description: |
Cas No. :129938-20-1
Quantity: 200Metric Tons Payment Method: T/T,Money Gram,Bank Transfer Product Description Dapoxetine Hydrochloride (Steroids) Dapoxetine Hydrochloride Synonyms: d-Dapoxetine hydrochloride; DL-Dapoxetine hydrochloride CAS: 129938-20-1 Assay: 98% min. Packing: 1kg net/foil bag or tin. Delivery: Express courier. MF: C9H7ClN2O5 MW: 258.62 Character: White to Off-White Cyrstalline Solid, odorless, slight sweet taste, Mp 175-177, optical rotation +128° Usage: Selective serotonin reuptake inhibitor (SSRI), pharmaceutical material, hormone. Male Enhancement Dapoxetine HCl (CAS: 1071929-03-7) Dutasteride (CAS: 164656-23-9) Finasteride (CAS: 98319-26-7) Yohimbine HCl (CAS: 65-19-0) Jinyang base Xinyang base Crepis base Applications: Dapoxetine, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 1864 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant. Treat male premature ejaculation and erectile dysfunction. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects. |
| CAS Registry Number: | 129938-20-1 |
| Synonyms: | ;DAPOXETINE HCL;Rimonabant 75000;LY-21044;((S)-(+)-N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride);(S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride;(1S)-N,N-Dimethyl-3-naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride;(S)-n,n-dimethyl-3-(naphthalene-1-yloxy)-1-phenylpropan-1-amine hydrochloride;(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride;(S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride;N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride (1:1);DL-Dapoxteine HCL;Hydrochloric acid Dapoxetine;S-Dapoxetine hydrochloride;D-Dapoxetine HCL;D-Dapoxetine Hydrochloride; |
| Molecular Formula: | C21H24ClNO |
| Molecular Weight: | 341.8744 |
| Molecular Structure: | 
|
| Company: | Shenzhen Simeiquan Bio-Technology Co.Ltd [ China ] |
| Contact: | Elsa |
| Tel: | 86-027-50756077 |
| Fax: | 86-027-50756077 |
| Email: | elsa@ycgmp.com |
-
Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.
