Promethazine hydrochloride
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| Post Date: | Jan 09,2018 |
| Expiry Date: | Jul 08,2018 |
| Detailed Description: |
Cas No. :58-33-3
Quantity: mass in stockKilograms Specs:white powder Price:negotiable USD Kilograms Payment Method: T/T, Western Union,Moneygram and Bitcoin. Description: Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. The drug has strong sedative and weak antipsychotic effects. It also reduces motion sickness and has antiemetic (via its action on the dopamine receptor D2) and anticholinergic properties. In some countries it is prescribed for insomnia when benzodiazepines are contraindicated. It is available in many countries under many brand names. Promethazine was developed in the mid 1940s when a team of scientists from Rhône-Poulenc laboratories were able to synthesize it from phenothiazine and a diamine side chain of diphenhydramine. Medical uses As a sedative For preoperative sedation and to counteract postnarcotic nausea To reduce nervousness, restlessness and agitation caused by psychiatric conditions (used for this purpose mainly in Europe) As antiallergic medication to combat hay fever (allergic rhinitis), etc., or to treat allergic reactions, alone or in combination with oral decongestants such as pseudoephedrine As an adjunct treatment for anaphylactoid conditions (IM/IV route preferred) Together with codeine or dextromethorphan against cough As a motion sickness or seasickness remedy when used with ephedrine or pseudoephedrine To combat moderate to severe morning sickness and hyperemesis gravidarum: In the UK, promethazine is drug of first choice, being preferred as an older drug with which there is a greater experience of use in pregnancy (second in line being metoclopramide or prochlorperazine). Previously, it was used as an antipsychotic, although it is generally not administered for this purpose now; promethazine has only approximately 1/10 of the antipsychotic strength of chlorpromazine. Treatment for migraines; however, other similar medications, like Compazine, have been shown to have a more favorable treatment profile, and are used almost exclusively over promethazine. |
| CAS Registry Number: | 58-33-3 |
| Synonyms: | ;Promethazine HCl;Promethazine Hydrochloride;N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine;N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride (1:1);10H-phenothiazine-10-ethanamine, N,N,α-trimethyl-, chloride; |
| Molecular Formula: | C17H20ClN2S |
| Molecular Weight: | 319.8726 |
| Molecular Structure: | 
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| Hazard Symbols: |  Xn:Harmful; |
| Risk Codes: | R22:; R36/37/38:; |
| Safety Description: | S26:; S36:; |
| Company: | Hengyang Desen Biotechnology Co., Ltd. [ China ] |
| Contact: | ava |
| Tel: | 86-18908446905 |
| Fax: | |
| Email: | ava@ycgmp.com |
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