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Tamoxifen Citrate CAS:54965-24-1 cheryl@chembj.com
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| Post Date: | Dec 31,2015 |
| Expiry Date: | Dec 30,2016 |
| Detailed Description: |
Quantity: 3000Kilograms Specs:cheryl@chembj.com Price:1 USD Kilograms Payment Method: T/T , Moneygram , Westunion,Bitcoin Nolvadex Gynocomastia Anti-Estrogen Steroids Tamoxifen Citrate CAS 54965-24-1 Tamoxifen Citrate CAS:54965-24-1 Molecular Formula: C26H29NO.C6H8O7 Molecular weight: 563.64 Melt Point: 140-144 oC EINECS: 259-415-2 Product Categories: Active Pharmaceutical Ingredients;Antitumors for Research and Experimental Use;Biochemistry;API's;Intracellular receptor;Steroid and Hormone;API;SOLTAMOX Mol File: 54965-24-1.mol storage temp. : 2-8°C Water Solubility : slightly soluble Appearance: white crystalline powder Usage: estrogen antagonist, antineoplastic Usage: anti-estrogen, protein kinase C inhibitor, beneficial cardiovascular effects, bone cancer treatment, induces DNA adduct formation Usage: An antiestrogen with potent anti-cancer and PKC inhibitory activities Biological Activity: Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30. Functions: Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine (anti-estrogen) therapy forhormonereceptor-positivebreast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked. |
| Company: | Hubei Yuancheng Saichuang Technology Co., Ltd [ China ] |
| Contact: | Cheryl |
| Tel: | 8618771024715 |
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| Email: | cheryl@chembj.com |
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