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2-Methoxyestradiol

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  Post Date: Feb 04,2015
  Expiry Date: Feb 04,2016
  Detailed Description: Cas No. :362-07-2 Product name: 2-Methoxyestradiol
CAS: 362-07-2
Molecular formula: C19H26O3
Molecular weight: 302.41
Description: 2-Methoxyestradiol (2ME2) is a natural metabolite of estradiol. As an experimental drug candidate, it is being developed under the tradename of Panzem. It prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis), hence it is an angiogenesis inhibitor.
It also acts as a vasodilator.
2ME2 is derived from estrogen, although it binds poorly to known estrogen receptors.
It induces apoptosis in some cancer cell lines.
It has undergone Phase 1 clinical trials against breast cancer.

  CAS Registry Number:

362-07-2

  Synonyms: ;2-Hydroxyestradol 2-methyl ether;2-Methoxyestra-1,3,5(10)-triene-3,17beta-diol;2-Methoxyestradiol-17beta;2ME2;NSC 659853;Panzem;UNII-6I2QW73SR5;(17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol;Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-;Estra-1,3,5(10)-triene-3,17beta-diol, 2-methoxy-;Estradiol, 2-methoxy-;2-methoxyestra-1(10),2,4-triene-3,17-diol;(17beta)-2-methoxyestra-1(10),2,4-triene-3,17-diol;(9xi,14xi,17beta)-2-methoxyestra-1(10),2,4-triene-3,17-diol;
  Molecular Formula: C19H26O3
  Molecular Weight: 302.4079
  Molecular Structure: 362-07-2 2-Methoxyestradiol

  Company: AUSMAUCO BIOTECH CO., LIMITED     [ China ]        
  Contact: john
  Tel: +8618060810639
  Fax:
  Email: plantsale@aus-bio.com
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