Home > Offer to Sell > Pharmaceuticals and Biochemicals > Auxiliaries and miscellaneous medicinal chemicals > 89778-27-8 Body Building Antiestrogen Raw Powder Toremifene Citrate
89778-27-8 Body Building Antiestrogen Raw Powder Toremifene Citrate
Inquiry
| Post Date: | Jun 13,2016 |
| Expiry Date: | Dec 10,2016 |
| Detailed Description: |
Cas No. :89778-27-8
Quantity: 100Kilograms Price:1000 USD Kilograms Payment Method: Bank Transfer, Western Union, Money Gram Toremifene Citrate Synonyms: FC 1157a; Fareston; NK 622; NSC 613680 CAS: 89778-27-8 Melting Point: 158-164 ºC Boiling Point: 535.1 ºC at 760 mmHg Density: 1.045g/cm3 Molecular Formula: C26H28ClNO·C6H8O7 Molecular Weight: 598.09 Appearance: White or almost white powder Packing: foil bag Payment: Bank Transfer, Western Union, Money Gram Express: EMS, DHL, FedEx, etc(door-to-door) Delivery: Safe & timely, around 1-3 days after payment Description: It is a member of a category, family, and class of drugs that are known as SERMs (Selective Estrogen Receptor Modulators). SERMs fall under an even broader category of drugs that are known as anti-estrogens, and the cousin family of SERMs (that also fall under anti-estrogens) are aromatase inhibitors, commonly abbreviated as AIs. SERMs include compounds such as Nolvadex and Clomid (Clomiphene Citrate). Aromatase inhibitors (AIs) include compounds such as Arimidex ) Aromasin, (Femara). Although the two fall under the category of anti-estrogens, they are both sub-categories that branch off into their own families, as SERMs and AIs differ greatly in their mechanism of action within the human body concerning how they control or block Estrogen. There has been much misunderstanding and misconception in previous decades as to what each of these do, and this should always be first clarified to the reader before describing Toremifene. Applications: Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene. It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels. Toremifene is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range. |
| CAS Registry Number: | 89778-27-8 |
| Synonyms: | ;(z)-4-chloro-1,2-diphenyl-1-(4-(2-(n,n-dimethylamino)ethoxy)phenyl)-1-butene ;2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin ;2-hydroxy-1,2,3-propanetricarboxylate(1:1) ;fareston ;fc1157a ;nk622 ; ;(z)-2-[4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy]-n,n-dimethyl-ethanamine 2-hydroxy-1,2,3-propanetricarboxylate ;TROPISETRON CITRATE ;2-[4-[(1Z)-4-CHLORO-1,2-DIPHENYL-1-BUTENYL]PHENOXY]-N,N-DIMETHYLETHANAMINE; |
| Molecular Formula: | C26H28ClNO·C6H8O7 |
| Molecular Weight: | 598.09 |
| Molecular Structure: | 
|
| Company: | Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [ China ] |
| Contact: | Jay |
| Tel: | 86-731-22290202 |
| Fax: | |
| Email: | zzychz04@chembj.com |
-
Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.
