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99% Procaine CAS 59-46-1 Local Anesthetic Apis Pain Killer
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| Post Date: | Nov 20,2017 |
| Expiry Date: | Nov 20,2018 |
| Detailed Description: |
Cas No. :59-46-1
Quantity: 1000Kilograms Specs:foil bag Price:1 USD Kilograms Payment Method: Western Union, money gram, t/t, bitcoin 99% Procaine CAS 59-46-1 Local Anesthetic Apis Pain Killer Quick Detail: Product name Procaine Procaine Alias 2-diethylaminoethyl 4-aminobenzoate Procaine CAS 59-46-1 Procaine EINECS 200-426-9 Procaine MF C13H20N2O2 Procaine MW 236.3101 Purity 99% Appearance White Crystalline Powder Description: Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as Procaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects. Procaine was first synthesized in 1905, shortly after amylocaine. It was created by the German chemist Alfred Einhorn who gave the chemical the trade name Procaine, from the Latin nov- (meaning new) and -caine, a common ending for alkaloids used as anesthetics. It was introduced into medical use by surgeon Heinrich Braun. Prior to the discovery of amylocaine and procaine, was the most commonly used local anesthetic.[citation needed] Einhorn wished his new discovery to be used for amputations, but surgeons preferred general anesthetic. Dentists, however, found it very useful. Einhorn was displeased by this[why?] and spent many years touring dental schools to advise them not to use it. Applications: Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest. Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity. COA Test Items Specification Test Results Appearance White crystals or a white crystalline powder Conform Identification ABE. It appears positive reaction Melting point 154degree~158degree 154degree~157degree Acidity PH 5.0~6.5 PH=5.9 Appearance of solution Clear and colourless Conform Loss on drying ≤0.5% 0.07% Heavy metals ≤0.0005% Conform Related substances ≤0.05% Conform Sulphated ash ≤0.1% 0.05% Assay ( on dry basis ) 99.0-101.0% 99.87% Conclusion Conform to BP2005 Usage: Procaine is a kind of local anesthetics. With low toxicity but quick and safe effects, procaine is suitable for local anesthesia, applied to the eye, ear, nose, teeth and other department operation, used for infiltration anesthesia, anesthesia and closed therapy supervisor. Procaine is also used in the production of procaine penicillin.Procaine causes loss of feeling (numbness) of skin and mucous membranes. Procaine is used as an injection during surgery and other medical and dental procedures. What's function of Procaine? Procaine works by inhibiting sodium channels in the cell membranes of neurons that enter the peripheral nerve. When the flow of sodium ions is interrupted, an action potential cannot be produced and the signal transduction is suppressed. The receptor site is believed to be located in the cytoplasmic (internal) part of the sodium channel. Procaine has also been shown to be binding or antagonistic to n-methyl-d-d-aspat (NMDA) receptors and nicotinic acetylcholine receptors and serotonin receptor-ion channel complexes. Anti-paining Anesthetic Anodyne Name CAS Tetracaine hydrochloride 50-41-9 Procaine 59-46-1 Tetracaine 94-24-6 Pramoxine Hydrochloride 637-58-1 Procaine HCl 1951-5-8 Lidocaine 137-58-6 Dibucaine hydrochloride 1961-12-1 prilocaine 721-50-6 Propitocaine hydrochloride 1786-81-8 Proparacaine hydrochloride 5875-6-9 Linocaine hydrochloride 6108-05-0 Articaine hydrochloride 23964-57-0 Levobupivacaine hydrochloride 27262-48-2 Ropivacaine hydrochloride 132112-35-7 Bupivacaine 2180-92-9 Bupivacaine hydrochloride 14252-80-3 Our Services 1) If you order raw powder, we can provide you with COA , Cook Recipes Of Steroid Oil , Feedback Of Other Customers 2) If you order Injectable Steroid Oil, we can provide you with Vials , Rubber Stoppers , Syringe Filters , Auto-Filter Machine , Crimper , Press Machine , Boxes, meanwhile, Usage Introduction and Feedback Of Other Customers will be offered also. 3)After your payment, shipping arrangement and package pictures will be provided within 24 Hours ; Tracking number will be provided within 36 Hours 4) For important parcel information, such as: Left Original Country , Arrived At Destination Country , Passed Customs , Out For Delivery , Delivered, those information will be sent to you timely. |
| CAS Registry Number: | 59-46-1 |
| Synonyms: | ;2-diethylaminoethyl 4-aminobenzoate;novocaine;Procaine base; |
| Molecular Formula: | C13H20N2O2 |
| Molecular Weight: | 236.3101 |
| Molecular Structure: | 
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| Company: | Hengyang Desen Biotechnology Co., Ltd. [ China ] |
| Contact: | Koala |
| Tel: | +86-073-48164621 |
| Fax: | 027-88608190-722 |
| Email: | koala@desen-nutrition.com |
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