AZD1152-HQPA
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| Post Date: | Apr 03,2015 |
| Expiry Date: | Apr 02,2016 |
| Detailed Description: |
Cas No. :722544-51-6
Quantity: 50g Specs:98% purity Payment Method: T/T, Western Union AZD-1152 is a novel acetanilide-substituted pyrazole-aminoquinazoline prodrug that is converted rapidly to the active drug AZD-1152 hydroxy-QPA (AZD1152-HQPA) in human plasma. AZD1152-HQPA is a specific inhibitor of the enzymatic activity of Aurora kinase, with selectivity for Aurora B (IC50 of 0.37 nM versus 1368 nM for Aurora B and A kinases, respectively); the inhibitor had even less activity against a panel of greater than 50 other serine-threonine and tyrosine kinases including FLT3, JAK2, and Abl. Preliminary studies showed that AZD-1152 was active against a variety of solid tumors including colon, breast,and lung cancers. |
| CAS Registry Number: | 722544-51-6 |
| Company: | Shanghai Sun-shineChemical Technology Co.,Ltd. [ China ] |
| Contact: | Rosie |
| Tel: | +86-027-59253327 |
| Fax: | 0086-27-5925 3326 |
| Email: | sales02@sun-shinechem.com |
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