Afatinib (BIBW 2992) CAS: 439081-18-2
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| Post Date: | Aug 31,2016 |
| Expiry Date: | Feb 27,2017 |
| Detailed Description: |
Cas No. :439081-18-2
Quantity: 0.01Kilograms Price:1.25 USD Kilograms Afatinib (BIBW 2992) CAS: 439081-18-2 E:steroidcn at ycgmp.com Sky:live:bella881030 Product Name: Afatinib Other Names:Afatinib;(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;4-[(3-chloro-4-fluorophenyl)aMino]-6-{[4-(N,N-diMethylaMino)-1-oxo-2-buten-1-yl]aMino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline;2-ButenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(diMethylaMino)-, (2E)-;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dime;Afatinib API;Afatinib(BIBW2992MA2);Afatinib (with 1 int.) Model No.: ATC-136 CAS No.: 439081-18-2 Molecular Formula: C24H25ClFN5O3 Molecular Weight: 485.94 Appearance: White or Nearly White Crystalline Powder Purity: 99%+ Product Specifications: Pharmaceutical Grade Product Description Afatinib (INN; trade name Gilotrif in the US and Giotrif in Europe, previously Tomtovok and Tovok) is a drug approved in United States, Europe, Taiwan, Mexico, Chile and Japan as well as other countries for the first-line treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It acts as an irreversible covalent inhibitor of the receptor tyrosine kinases epidermal growth factor receptor (EGFR) and erbB-2 (HER2). Applications/Usage It has received regulatory approval for use as a treatment for non-small cell lung cancer, although there is emerging evidence to support its use in other cancers such as breast cancer. |
| CAS Registry Number: | 439081-18-2 |
| Synonyms: | ;BIBW 2992;BIBW-2992;Tovok;2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-;(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide;Afatinib;(E)-N-(7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;BIBW2992;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-dime; |
| Molecular Formula: | C24H25ClFN5O3 |
| Molecular Weight: | 485.9384 |
| Molecular Structure: | 
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| Company: | Gongchuang Technology Co.,Ltd [ China ] |
| Contact: | Bella Lee |
| Tel: | 86-27-50755950 |
| Fax: | |
| Email: | steroidcn@ycgmp.com |
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