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Beclomethasone Dipropionate(Aldecin,Proctisone,Beconase)

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  Post Date: May 11,2014
  Expiry Date: Nov 07,2014
  Detailed Description: English name :

Beclomethasone Dipropionate (Aldecin, Proctisone, Beconase)

Properties:

White or white crystalline powder , odorless . Insoluble in water ; soluble in ethanol ( 1:60 ) chloroform ( 1:8 ) .

The role and mechanism of action :

This product is a potent topical corticosteroids, has a high specificity for lung , bronchial smooth muscle relaxation stronger . Its effective mechanism is a multi- link : ① anti-inflammatory effects , partial remission airway inflammation ; ② suppress allergic reactions, allergic mediator release so reduced activity decreased ; ③ inhibition of phospholipase A2, so that leukotrienes and prostaglandins reduce the generation of ; ④ enhanced β receptor reactivity. Inhalation bronchial asthma has a good effect on the daily 0.4mg that can effectively control asthma attacks , its efficacy and oral 7.5mg prednisone equivalent, asthma action can be maintained 4-6h. Inhalation of this product work slowly , 10d after breathing increased and reached a peak before , it had long-term oral corticosteroids by inhalation of the product , the need to continue oral, two weeks later in order to gradually reduce the dose of oral corticosteroids . Status asthmaticus who , because they can not inhale enough of the drug , efficacy is often poor , should not be used . Airway inflammation obstruction , this product should not reach the small airways , often can not be effective, control inflammation after oral administration should then maintain the efficacy of the product inhalation . This product is absorbed in the body can quickly metabolic inactivation , does not show the absorption effect, it is little systemic adverse reactions , generally on the pituitary - adrenal function has no effect.


  Company: Hubei Pharmaceutical Co., Ltd. Shi Nan ninety-five     [ China ]        
  Contact: kevin peng
  Tel: +86-027-13554447107
  Fax:
  Email: 13554447107@163.com
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