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Betamethasone Acetate

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  Post Date: Aug 19,2015
  Expiry Date: Feb 15,2016
  Detailed Description: Cas No. :987-24-6 Betamethasone Acetate
email:jaymee at ycphar dot com.
English Synonyms: Betamethasone 21-acetate; 9ALPHA-FLUORO-16BETA-METHYL-11BETA, 17ALPHA, 21-TRIHYDROXY-1, 4-PREGNADIENE-3, 20-DIONE 21-ACETATE; 9a-fluoro-16b-methyl-11b, 17a, 21-trihydroxy-1, 4-pregnadiene-3, 20-dione 21-acetate; 1, 4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17, 21-TRIOL-3, 20-DIONE 21-ACETATE; BETAMETHASONE 21-ACETATE; BETAMETHASONE ACETATE; 9-fluoro-11beta, 17, 21-trihydroxy-16beta-methylpregna-1, 4-diene-3, 20-dione 21-acetate; Betamethasone acetate BP/USP/EP; BETAMETHASONE ACETATE EPB(CRM STANDARD)
CAS NO.: 987-24-6
Assay: 98%
Molecular Formula: C24H31FO6
Molecular Weight: 434.5
Quality Standard: EP5/USP28
Packing: Foil bag
Usage: Mainly used for anti-inflammatory and anti-allergy. Apply to rheumatoid arthritis and various skin diseases
Appearance: White crystalline powder
Betamethasone acetate is a white to creamy white, odorless powder. It is practically insoluble in water, but freely soluble in acetone, and is soluble in alcohol and in chloroform.

Description:
Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension, USP is a sterile aqueous suspension containing betamethasone 3 mg per milliliter as betamethasone sodium phosphate, and betamethasone acetate 3 mg per milliliter. Inactive ingredients per mL: dibasic sodium phosphate 7.1 mg; monobasic sodium phosphate 3.4 mg; edetate disodium 0.1 mg; and benzalkonium chloride 0.2 mg as a preservative. The pH is adjusted to between 6.8 and 7.2.
The formula for betamethasone sodium phosphate is C22H28FNa2O8P and it has a molecular weight of 516.40. Chemically, it is 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-(disodium phosphate).

The formula for betamethasone acetate is C24H31FO6 and it has a molecular weight of 434.50. Chemically, it is 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate.
Betamethasone sodium phosphate is a white to practically white, odorless powder, and is hygroscopic. It is freely soluble in water and in methanol, but is practically insoluble in acetone and in chloroform.
Betamethasone acetate is a white to creamy white, odorless powder that sinters and resolidifies at about 165ºC, and remelts at about 200ºC-220ºC with decomposition. It is practically insoluble in water, but freely soluble in acetone, and is soluble in alcohol and in chloroform.

Application:
BETAMETHASONE (bay ta METH a sone) is a corticosteroid. It helps to reduce swelling, redness, itching, and allergic reactions. It is used to treat asthma, allergies, arthritis, Crohn's disease, and ulcerative colitis. It is also used for other conditions, like blood disorders and diseases of the adrenal glands.

  CAS Registry Number:

987-24-6

  Synonyms: ;Betamethasone Acetate;(8xi,10xi,11beta,13xi,16beta)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate;(11beta,16beta)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate;
  Molecular Formula: C24H31FO6
  Molecular Weight: 434.4977
  Molecular Structure: 987-24-6 betamethasone 21-acetate
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
  Safety Description: S22:;
S36:;

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