Bilberry extract
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| Post Date: | May 29,2013 |
| Expiry Date: | May 29,2014 |
| Detailed Description: |
Cas No. :537-42-8
Quantity: 30 Specs:99% Price:650 USD Kilograms Payment Method: T/T, L/C, Western union, Paypal Pterostilbene is... The Next Generation Resveratrol Pterostilbene , homologues of resveratrol, but its anti-fungal activity is 5 times as resveratrol Pterostilbene, trans-3,5-Dimethoxy-4′ -hydroxystilbene, is a multi-stilbene compounds for resveratrol in the same series. Can be widely founded in grapes, blueberries and other natural plant. Recent studies have shown that pterostilbene has antioxidant activity, it can clear the free radicals. In addition, it has strong anti-fungal activity (anti-fungal activity is 5 times as resveratrol), cancer chemopreventive activity, induced apoptosis in MDR cell activity, PPAR activity and so excited. Pterostilbene is also the precursor of resveratrol which has a multifunctional health effects. Therefore, it shouws out its Important research value and good prospects Introduction: Pterostilbene is a stilbenoid chemically related to resveratrol and is found in blueberries and grapes. It belongs to the group of phytoalexins, agents produced by plants to fight infections. Based on animal studies it is thought to exhibit anti-cancer, anti-hypercholesterolemia, anti-hypertriglyceridemia properties, as well as fight off and reverse cognitive decline. It is believed that the compound also has anti-diabetic properties, but so far very little has been studied on this issue. Phytochemical Profile of Pterostilbene Product name Pterostilbene CAS# 537-42-8 Assay: 98.5% Appearance White to off-white fine crystal Molecular Weight 256.299 Molecular Formula C16H16O3 Other Names: Methylated Resveratrol Dimethoxyresveratrol 3’,5’-Dimethoxy-4-stilbenol 3,5-Dimethoxy-4’-hydroxy-trans-stilbene 4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol Function Pterostilbene antioxidant by Ray Sahelian, M.D. Pterostilbene is similar to the antioxidant resveratrol found in grapes and red wine, which also has anticancer activity. Pterostilbene is also present in grapes, but it is more abundant in blueberries. In the test tube and in animals that pterostilbene is capable of lowering cholesterol levels. If you would like to purchase a Resveratrol supplement. Pterostilbene and colon cancer A natural antioxidant abundant in blueberries called pterostilbene may help prevent colon cancer. Dr. Bandaru S. Reddy, chemical biologist at Rutgers University, Piscataway, New Jersey, induced colon cancer in 18 rats and then fed the animals a balanced diet, with or without pterostilbene (40 mg/kg of diet). At the end of the study, the nine animals that received pterostilbene supplement had 57-percent fewer pre-cancerous growths in the colon compared with the animals that were fed a balanced diet only. Pterostilbene also suppressed the growth of cells in the colon and inhibited certain genes involved in inflammation, both of which are considered risk factors for colon cancer. Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats. Clin Cancer Res. 2007 Jan 1;13(1):350-5.Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA. Laboratory animal model studies have provided evidence that stilbenes, phenolic compounds present in grapes and blueberries, play a role in inhibiting the risk of certain cancers. Pterostilbene, a naturally occurring stilbene from blueberries, was tested for its preventive activity against colon carcinogenesis. Experiments were designed to study the inhibitory effect of pterostilbene against the formation of azoxymethane-induced colonic aberrant crypt foci (ACF) preneoplastic lesions in male F344 rats. The results of the study suggest that pterostilbene, a compound present in blueberries, is of great interest for the prevention of colon cancer. Pterostilbene as antioxidant The antioxidant role of pterostilbene in streptozotocin-nicotinamide-induced type 2 diabetes mellitus in Wistar rats. J Pharm Pharmacol. 2006 Nov;58(11):1483-90. Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, Tamilnadu, India. The antioxidant effect of pterostilbene on streptozotocin-nicotinamide-induced diabetic rats has been assessed. The activity of superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and reduced glutathione was significantly decreased in liver and kidney of diabetic animals when compared with normal control. There were significant improvements in these activities after treatment with pterostilbene at a dose of 40 mg kg(-1) for six weeks. The increased levels of lipid peroxidation measured as thiobarbituric acid reactive substances (TBARS) in liver and kidney of diabetic rats were also normalized by treatment with pterostilbene. Chronic treatment of pterostilbene remarkably reduced the pathological changes observed in liver and kidney of diabetic rats. These results indicated the antioxidant property of pterostilbene. |
| CAS Registry Number: | 537-42-8 |
| Synonyms: | ;trans-3',5'-Dimethoxy-4-stilbenol;3,5-Dimethoxy-4'-hydroxy-trans-stilbene;4-(E)-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol;4-Stilbenol, 3',5'-dimethoxy-, (E)-;Phenol, 4-(2-(3,5-dimethoxyphenyl)ethenyl)-, (E)-;Trans-3,5-dimethoxy-4'-hydroxystilbene;pterocarpus marsupium;3,5-dimethoxy-4'-hydroxystilbene;3',5'-Dimethoxy-4-stilbenol;pterostilbene; |
| Molecular Formula: | C16H16O3 |
| Molecular Weight: | 256.2964 |
| Molecular Structure: | 
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| Hazard Symbols: |  Xi:Irritant; N:Dangerous for the environment; |
| Risk Codes: | R41:; R51/53:; |
| Safety Description: | S26:; S39:; S61:; |
| Company: | Wu xi Cima Science Co.,Ltd [ China ] |
| Contact: | jennifer |
| Tel: | 86-15190226794 |
| Fax: | |
| Email: | cimasci001@gmail.com |
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