Buff
Inquiry
| Post Date: | Apr 03,2018 |
| Expiry Date: | Sep 30,2018 |
| Detailed Description: |
Buff is the replacement of FUF. It is free for your testing, it is good quality and in stock, welcome to your inquire.
[1] and has been sold as a designer drug. [2] It has an ED50 value of 0.02 mg/kg in mice. [3] This makes it approximately five times less potent than fentanyl. (4)Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear. [5]Life-threatening adverse reactions caused by furanylfentanyl use have been observed in Sweden and Canada. [6] At least seven deaths in Cook County, Illinois, have been linked to furanylfentanyl in 2016, with additional deaths in suburban Chicago in 2017. It is an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selective agonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphine in animal models. It is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that it was the most active. became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures.Although not used medically, the selective kappa ligands are used in research. email:sunny（at）chiyangbio.com |
| Company: | chiyang biological technology co,limited [ China ] |
| Contact: | sunny |
| Tel: | 86-311-5326796 |
| Fax: | |
| Email: | sunny@chiyangbio.com |
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