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Calcium Gluconate CAS 299-28-5 as Mineral Supplement (jerryzhang001@chembj.com)

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  Post Date: Mar 24,2017
  Expiry Date: Mar 24,2018
  Detailed Description: Cas No. :299-28-5 Calcium Gluconate CAS 299-28-5 as Mineral Supplement


Product Name: Calcium gluconate;
Synonyms: CALCIUM D-GLUCONATE;CALCIUM GLUCONATE;GLUCONIC ACID CALCIUM SALT;GLUCONIC ACID HEMICALCIUM SALT;D-GLUCONIC ACID CALCIUM SALT;D-GLUCONIC ACID HEMICALCIUM SALT;2,3,4,5,6-PENTAHYDROXYCAPROIC ACID HEMICALCIUM SALT;calcicol;
CAS: 299-28-5;
MF: C12H22CaO14;
MW: 430.37;
EINECS: 206-075-8;
Product Categories: Biochemistry;Ca (Calcium) Compounds;Classes of Metal Compounds;Glucose;Sugar Acids;Sugars;Typical Metal Compounds;Food & Flavor Additives;ANTIFEBRIN;stabilizer;


Melting point: 195°C;
Water Solubility: 3.3 g/100mL;
HS Code: 29181600;

Chemical Properties: white crystalline powder or granules;


Description:

Calcium gluconate is a mineral supplement and medication.[1] As a medication it is used by injection into a vein to treat low blood calcium, high blood potassium, and magnesium toxicity.[2][1] Supplementation is generally only required when there is not enough calcium in the diet.Supplementation may be done to treat or prevent osteoporosis or rickets. It can also be taken by mouth but is not recommended by injection into a muscle.


Medical uses:

Low blood calcium

10% calcium gluconate solution (given intravenously) is the form of calcium most widely used in the treatment of low blood calcium. This form of calcium is not as well absorbed as calcium lactate,and it only contains 0.93% (930 mg/dl) calcium ion (defined by 1 g weight solute dissolved in 100 ml solvent to make 1% solution w/v). Therefore, if the hypocalcaemia is acute and severe, calcium chloride is given instead.

High blood potassium

Calcium gluconate is used as a cardioprotective agent in high blood potassium, with one alternative being use of calcium chloride.It is recommended with the potassium levels are high (>6.5 mmol/l) or there are changes of high blood potassium on the electrocardiogram (ECG);

Though it does not have an effect on potassium levels in the blood, it reduces the excitability of cardiomyocytes thus lowering the likelihood of developing cardiac arrhythmias.

Magnesium sulfate overdose

It is also used to counteract an overdose of Epsom Salts magnesium sulfate,which is often administered to pregnant women in order to prophylactically prevent seizures (as in a patient experiencing preeclampsia). Magnesium sulfate is no longer given to pregnant women who are experiencing premature labor in order to slow or stop their contractions (other tocolytics are now used instead due to better efficacy and side effect profiles).[citation needed] Excess magnesium sulfate results in magnesium sulfate toxicity, which results in both respiratory depression and a loss of deep tendon reflexes (hyporeflexia). Calcium gluconate is the antidote for magnesium sulfate toxicity.

Hydrofluoric acid burns

Gel preparations of calcium gluconate are used to treat hydrofluoric acid burns. This is because calcium gluconate reacts with hydrofluoric acid to form insoluble, non-toxic calcium fluoride.

Black widow spider bites

Historically, IV calcium gluconate was used as an antidote for black widow spider envenomation, often in conjunction with muscle relaxants. This therapy, however, has since been shown to be ineffective.

  CAS Registry Number:

299-28-5
  Synonyms: ;Gluconic acid calcium salt;calcii gluconas;calcium d-gluconate;d-gluconic acid calcium salt;hexonic acid, calcium salt (2:1);calcium bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate] (non-preferred name);calcium bis(2,3,4,5,6-pentahydroxyhexanoate) (non-preferred name);Calcium gluconate anhydrous;CALCIUM GLUCOHEPTONATE;
  Molecular Formula: 2(C6H11O7)·Ca
  Molecular Weight: 430.38
  Molecular Structure: 299-28-5 Calcium Gluconate
  Safety Description: S24/25:;

  Company: Nanjing Bangnuo Biotechnology Co., Ltd.     [ China ]        
  Contact: Jerry Zhang
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