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Cefotaxime Sodium

Inquiry
  Post Date: Oct 11,2018
  Expiry Date: Apr 09,2019
  Detailed Description: Cas No. :64485-93-4 Payment Method: T/T D/A D/P L/C
64485-93-4 Cefotaxime sodium
Pass GMP USP34
Molecular Formula:C16H16N5NaO7S2
Molecular Weight:477.44CAS:64485-93-4
EINECS:264-915-9
Appearance: This product is white, almost white or yellowish white crystalline powder; odorless or slight special smell. It is free soluble in water, slightly soluble in ethanol, insoluble in chloroform.
Indications and Usage:
Treatment of infections of lower respiratory tract including pneumonia, urinary tract, skin and skin structures, bone and joints; treatment of bacteremia/septicemia, CNS infections, intra-abdominal infections including peritonitis, gynecological infections including pelvic inflammatory disease, endometritis and pelvic cellulitis caused by susceptible strains of specific microorganisms; perioperative prophylaxis.
ITEMS
SPECIFICATION
RESULTS
Appearance
White to pale yellow Crystalline Powder
Passed
Identification
IR Spectrum
HPLC RT
Sodium
Passed
Passed
Passed
Clarity
Clear
Passed
Color of Solution
NMT 0.2(430mm,10% solution)
Passed
Specific optical rotation
+56°~+64°
+61°
PH
4.5~6.5
5.5
Loss on drying
≤3.0%
2.7%
Chromatographic purity
Individual impurity
Total impurity

≤1.0%
≤3.0%

≤0.6%
≤2.0%
Sterility
Sterile
Passed
Bacterial Endotoxins
NMT 0.20 USP EU/mg
Passed
Particulate matter
≥10um NMT 6000
≥25 um NMT 600
Passed
Passed
Assay(HPLC)
916-964μg/mg
940μg/mg
Storage Condition
Preserve in tight container.

  CAS Registry Number:

64485-93-4
  Synonyms: ;Cefotaxime sodium salt;Cefotaxime sodium;Claforan;sodium salt of 7-[2-(2-amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7 (Z)-(O-methyloxime), acetate (ester);(6r-(6alpha,7beta(z)))-3-((acetyloxy)methyl)-(((2-amine-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylic acid monosodium salt;sodium (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2E)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-8-oxo-, sodium salt, (6R,7R)- (1:1);cefotaxim sodium;
  Molecular Formula: C16H17N5NaO7S2
  Molecular Weight: 478.4547
  Molecular Structure: 64485-93-4 cefotaxim sodium salt

  Company: Sinoright International Trade Co. Ltd.     [ China ]          
  Contact: Harry Du
  Tel: 0086-411-86596755 39210844 130
  Fax: 0086-411-86596060 39210855
  Email: harry.du@sinoright.net
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