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Ceftiofur sodium

Inquiry
  Post Date: Jan 15,2019
  Expiry Date: Jul 14,2019
  Detailed Description: Cas No. :19774-82-4 Items Specifications Results
Characters
Appearance White or almost white, fine crystalline powder conforms
Solubility Very slightly soluble in water, freely soluble in methylene chloride, soluble methanol, sparingly soluble in ethanol(96%) conforms
Identification
A) IR Conforms to Amiodarone Hydrochloride CRS Conforms
B) Chlorides It gives reactions of chlorides Conforms
Appearance of solution clear, NMT GY5 Conforms
Melting Range 159~163°C 159.0~160.0°C
pH 3.2~3.8 3.63
Impurity H (by TLC) NMT 0.02% <0.02%
Related Substance (by HPLC )
Impurity A NMT 0.20% 0.07%
Impurity B NMT 0.20% 0.10%
Impurity C NMT 0.20% conforms
Impurity D NMT 0.20% 0.05%
Impurity E NMT 0.20% 0.03%
Impurity F NMT 0.20% conforms
Impurity G NMT 0.20% 0.01%
Unspecified impurities NMT 0.20% 0.02%
Total impurities NMT 0.20% 0.34%
Iodides NMT 150ppm <150ppm
Heavy metals NMT 20ppm <20ppm
Loss on drying NMT 0.5% 0.08%
Sulphated ash NMT 0.1% 0.02%
Assay 98.5%~101.0% 100.00%
Residual Solvents
Ethanol NMT5000ppm 782ppm
Toluene NMT890ppm 94ppm
Conclusion The results can conforms with the EP6

  CAS Registry Number:

19774-82-4

  Synonyms: ;Amiodarone hydrochloride;Amiodarone hydrochlorde;
  Molecular Formula: C25H29I2NO3·HCl;C25H30ClI2
  Molecular Weight: 681.78
  Molecular Structure: 19774-82-4 Amiodarone HCL
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R20/21/22:;
  Safety Description: S36:;

  Company: Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd     [ China ]          
  Contact: linda.wang
  Tel: 86-27-50661279
  Fax: 86-27-87569548
  Email: sales04@benjaminpharmchem.com
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