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Colistin Sulphate

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  Post Date: Apr 15,2024
  Expiry Date: Apr 15,2025
  Detailed Description: Cas No. :1264-72-8 Quantity: 1,000Metric Tons
Specs:EP / CP
Payment Method: L/C,D/P,T/T

Colistin Sulphate

 

 Colistin (Polymyxin E) is polymyxin antibiotic isolated from culture fluid of Bacillus polymyxa var colistinus bacteria in soil. Colistin is effective against most Gram-negative bacilli such as E-coil, Serpulina Hyodysenteriae, Salmonella Pullorum  and also effective on Pseudomonas aeruginosa.

 

[Molecular Formula]    2(C52H98N16O13) · 5(H2SO4) 

 

[Molecular Weight]      2801.27

 

[Specifications for EP7] 

 

Test Items

Specifications

Appearance

White or almost white, hygroscopic powder

Specific Rotation

-63º to -73º

Identification

Positive

pH

4.0 to 6.0

Loss on Drying

3.5% max

Sulphate (Dried Basis)

16.0 to 18.0 %

Sulphated Ash

1.0% max

Total Impurities

23.0% max

Assay HPLC (Dried Basis)

Sum of E1,E2,E1-I,E1-7MOA,E3

77.0% min

Potency (Dried Basis)

19,000 IU/mg min

 

 

[Characteristic] 

 

  1)  Improve growth performance and conversion rate of livestock & poultry;

  2)  Inhibit Gram-negative bacteria at growth duration or dormancy state;

  3)  Prevent bacterial diarrhea & synergistic effects with other antibiotics;

  4)  No cross tolerance with broad range of antibacterial agent;

  5)  Little absorbed by intestine and stomach, no residue.

 

 [Recommended dosage]   g/ton of complete feed

 

Target Animals

Colistin Sulphate

Withdrawal Period

Swine

<2 months

2(60MU) – 20(600MU)

7 Days

2-4 months

2(60MU) – 40(1,200MU)

Poultry

< 70 days

2(60MU) – 20(600MU)

Cattle

< 3 months

5(150MU) – 40(1,200MU)

Note: 1ug of Colistin is equivalent to 30 units of Colistin; MU = Million Unit

 [Precaution] 

 

 1)   May cause damage in kidney function by overdosing;

 2)  Prohibited to use during laying period. 

 

 [Storage]   It should be kept cool and dry in well-closed original package.

 

 [Package]   25kg Drum net each

 

 [Shelf Life]   Two Years

  CAS Registry Number:

1264-72-8
  Synonyms: ;Colistin Sulphate;n-[3-amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide sulfate;N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methyloctanamide sulfate (1:1);N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide;belcomycin;
  Molecular Formula: C52H98N16O13
  Molecular Weight: 1155.4339
  Molecular Structure: 1264-72-8 colistin sulfate
  Hazard Symbols:  T:Toxic;
  Risk Codes: R25:;
  Safety Description: S45:;

  Company: Zhejiang University Sunny Nutrition Technology Co.,Ltd.     [ China ]          
  Contact: Mrs. Jessica Wang
  Tel: +86-571-88219255 88212050
  Fax: +86-571-88210515
  Email: sunny@sunnynutri.com
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