Dihydromyricetin

 CAS NO： 27200-12-0

Latin Name ：Dihydromyricetin/ampelopsin,DH M

Plant Origin ：Tender branches and leaves of big leaf snake grape in grape family plant（Commonly known as rattan tea）。

Alias： Ampelopsin

Chemical Name:（2 r, 3 r) - 3, 5, 7 - three hydroxy - 2 - (3 3-5 - three hydroxy phenyl) benzene and dihydro pyran - 4 – ketone

Molecular Formula: C15H12O8，（320.25）

Appearance: Yellow powder

Main Ingredients: Dihydromyricetin 98%

Physical Property :This product is a white needle crystal (ethanol),easily solve in hot water, hot ethanol and acetone, soluble in ethanol and methanol, very slightly soluble in ethyl acetate can not solve in chloroform, petroleum ether. Microherb research shows that dihydromyricetin has a good thermostability, But with the rise of temperature greater than 100 ℃dihydromyricetin will occur irreversible oxidation reaction. It is stable in neutral and partial acid conditions.

Efficacy : （1）Antibacterial Action：Pharmacological experiments show that，dihydromyricetin has a bacteriostatic action to hay bacillus, salmonella, staphylococcus aureus, escherichia coli, gas bacillus, beer yeast, sticky red yeast, mould, aspergillus Niger and aspergillus flavus, wool mildew and rhizopus, especially for gram positive and gram negative bacteria aureus and bacillus has obvious effect

（2）Regulation effect to blood sugar, blood lipid：pharmacology experiment of Lavage in mice shows can significantly inhibited the increase of blood sugar induced by four oxygen pyrimidine, epinephrine, streptozotocin, the increase serum insulin levels, significantly reduce of lymphocytes infiltration, Inflammatory reaction, significantly increased Islet number in pancreatic tissue. Dihydromyricetin also can low the Hyperglycemia rat serum, triacylglycerol, induced by streptozotocin. But it has no obvious effect to the content of serum total cholesterol (TC) and high density lipoprotein cholesterol (HDL2C)

（3）Function of liver protect：Dihydromyricet in can protect the liver cells of in vitro cultured rat which has carbon tetrachloride toxic damage and mice liver injury induced by D2galactosamine and lipopolysaccharide. Besides, it can improve the increase of serum lactate dehydrogenase activity which is caused by hepatocellular injury ,inhibite the formation of collagen fibers of liver cirrhosis M cells so that to protect liver, greatly reduce the liver damage caused by alcohol and make liver recover soon. Microherb research shows that dihydromyricetin can protect live, accelerated decomposition of ethanol metabolic product acetaldehydeand turn it into non-toxic substances so that can reduce the damage to the liver cell. It works quickly and last long. So it indeed a good matter to protect liver and dispel the effects of alcohol.

（4）Antioxygenation： dihydromyricetin98% can restrain the produce of malondialdehyde in rat myocardial,liver and brain homogenate, and this kind of function will strengthen as the increase of the concentration of dihydromyricetin. dihydromyricetin99% has a good clearance to diphenyl trinitrobenzene hydrazine (DPPH) free radicals in test system. It can obviously inhibit the generation of MDA in oil, With two hydrogen arbutus element purity (60% ~ 90%) increase antioxidant effect will be enhanced To animal oil and vegetable oil it all has a strong antioxidant effect.

（5）Anti-tumor Effect：In recent years, anti-tumor pharmacodynamics study found that one of the active constituents, snake grape grain small molecule compounds has a strong anti-cancer effect In vitro antitumor action research found that the compound can inhibit tumor vascular growth, adjust the enhancement of cell immune function and effects to enhance the tumor treatment effect and improve the patient's life, in leukemia and nasopharyngeal carcinoma and tumor model test study shows it has an obvious inhibitory tumor effect. Application Show tooth snake grape also called rattan tea is the traditional folk medicine. 

Packing Specifications: Plastic bags inside and cardboard barrels outside，15kg/barrel、25kg/barrel Or according to the customer request

27200-12-0